Results 101 to 110 of about 3,176,564 (314)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Artefacts of PET/CT images

open access: yesBiomedical Imaging and Intervention Journal, 2006
Positron emission tomography (PET) is a non-invasive imaging modality, which is clinically widely used both for diagnosis and accessing therapy response in oncology, cardiology and neurology.Fusing PET and CT images in a single dataset would be useful for physicians who could read the functional and the anatomical aspects of a disease in a single shot ...
Pettinato, C   +9 more
openaire   +2 more sources

CT imaging of an Egyptian mummy [PDF]

open access: yes, 1993
Over the last few years various research groups around the world have employed X-ray Computed Tomography (CT) imaging in the study of mummies – Toronto-Boston (1,2), Manchester(3).
Hughes, Stephen W.
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Geometric Misalignment Calibration and Detector Lag Effect Artifact Correction in a Cone-Beam Flat Panel micro-CT System for Small Animal Imaging [PDF]

open access: yes, 2022
The cone-beam flat panel micro-CT is a high definition imaging system. The CT system is affected by several imperfections and problems, that might lead to serious artifacts that deteriorate the quality of the reconstructed image.
Di Sopra, Lorenzo
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

A note on feature selection for polyp detection in CT colonography [PDF]

open access: yes, 2006
In this paper we describe a computer aided detection (CAD) algorithm for robust detection of polyps in computed tomography (CT) colonography. The devised algorithm identifies suspicious polyp candidate surfaces using the surface normal intersection ...
Chowdhury, Tarik A.   +11 more
core   +2 more sources

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

CT imaging of ascaris lumbricoides

open access: yesJournal of the Belgian Society of Radiology, 2010
A 37-year-old man was referred to the department of internal medicine for chronic fever, asthenia and loss of weight. He had no relevant medical history but reported frequent travels to Africa. Abdominal-CT study with contrast agent injection and oral digestive opacification was performed and revealed pleuroperitoneal and pericardial effusions with ...
Deprez, F C, Pauls, C, Puttemans, T
openaire   +5 more sources

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