Results 81 to 90 of about 3,326,582 (312)

Tumour–capsule interface measured on 18F-DCFPyL PSMA positron emission tomography/CT imaging comparable to multi-parametric MRI in predicting extra-prostatic extension of prostate cancer at initial staging

, 2020
Introduction: Nerve-sparing prostatectomy is recommended in cases of organ-confined prostate cancer but is generally contraindicated in patients with suspected extra-prostatic extension (EPE).
Somasundaram, Arjuna, Collie, Leesa, Leesa Collie, Brauchli, Damian, Arjuna Somasundaram, Damian Brauchli, Dalveer Singh, Singh, Dalveer, Chabert, Charles, Charles Chabert   +9 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Perfusion CT imaging of the liver: review of clinical applications [PDF]

, 2014
Perfusion computed tomography (CT) has a great potential for determining hepatic and portal blood flow; it offers the advantages of quantitative determination of lesion hemodynamics, distinguishing malignant and benign processes, as well as providing ...
Kantarci, M., Pirimoglu, B., Kizrak, Y., KIZRAK, Yesim, Neşat Çullu, Ogul, H., Berhan Genç, Cullu, Nesat, Berhan Pirimoğlu, Kantarci, Mecit, Yilmaz, O., Hayri Oğul, Mecit Kantarcı, Ömer Yılmaz, Nevzat Karabulut, Çullu, N., YILMAZ, Ömer, Yeşim Kızrak, PIRIMOGLU, Berhan, Genç, B., Karabulut, Nevzat, OĞUL, Hayri, GENC, Berhan   +22 more
core   +1 more source

Time-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome

Diagnostics
Background: Hematoma expansion (HE) following an intracerebral hemorrhage (ICH) is a modifiable risk factor and a treatment target. We examined the association of HE with neurological deterioration (ND), functional outcome, and mortality based on the ...
Gaby Abou Karam, Min-Chiun Chen, Dorin Zeevi, Bendix C. Harms, Victor M. Torres-Lopez, Cyprien A. Rivier, Ajay Malhotra, Adam de Havenon, Guido J. Falcone, Kevin N. Sheth, Seyedmehdi Payabvash   +10 more
doaj   +1 more source

Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography

Molecules, 2016
Reactive oxygen species (ROS) play important roles in cell signaling and homeostasis. However, an abnormally high level of ROS is toxic, and is implicated in a number of diseases.
Wenjie Zhang, Zhengxin Cai, Lin Li, Jim Ropchan, Keunpoong Lim, Nabil E. Boutagy, Jing Wu, John C. Stendahl, Wenhua Chu, Robert Gropler, Albert J. Sinusas, Chi Liu, Yiyun Huang   +12 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Squamous Cell Carcinoma: PET/CT and PET/MRI of the Pretreatment and Post-Treatment Neck

, 2019
The incidence of head and neck cancer continues to rise annually, most commonly squamous cell carcinoma (SCCa). Advances in imaging techniques have improved diagnostic accuracy with important ramifications for initial staging and post-treatment ...
Mosier, Kristine, Traylor, Katie S., Koontz, Nicholas   +2 more
core   +1 more source

Variability of the posteromedial meniscocapsular junction of the knee on MRI: Pitfall to imaging diagnosis of ramp lesions

European Journal of Radiology Open
Objective: A ramp lesion describes injury at the junction of the posterior horn medial meniscus and posteromedial joint capsule occurring with anterior cruciate ligament deficiency.
Jack Porrino, Eric Marten, Michael L. Richardson, Jay Moran, Colby Shreve, Hyojeong Lee, Andrew Haims   +6 more
doaj   +1 more source

Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children

NeuroImage: Clinical, 2016
Background: Preterm (PT) children show early cognitive and language deficits and display altered cortical connectivity for language compared to term (T) children.
Megan A. Rowlands, Dustin Scheinost, Cheryl Lacadie, Betty Vohr, Fangyong Li, Karen C. Schneider, R. Todd Constable, Laura R. Ment   +7 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source