Results 61 to 70 of about 3,176,564 (314)

Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and 11C-UCB-J PET study

Frontiers in Human Neuroscience, 2023
Introduction: Resting-state network (RSN) connectivity is a widely used measure of the brain’s functional organization in health and disease; however, little is known regarding the underlying neurophysiology of RSNs.
Xiaotian T. Fang, Tommaso Volpi, Sophie E. Holmes, Irina Esterlis, Irina Esterlis, Richard E. Carson, Patrick D. Worhunsky   +6 more
doaj   +1 more source

CT-PET guided target delineation in head and neck cancer and implications for improved outcome [PDF]

, 2010
Aim: Fifty percent of patients with squamous cell carcinoma of the Head and Neck develop loco-regional recurrence after treatment. Factors leading to this failure are most likely altered intra-tumoural glucose metabolism and increased hypoxia ...
Moule, R.N.
core  

Comparison of propagation-based phase-contrast CT and absorption-based CT for breast imaging using synchrotron radiation

, 2020
Propagation-based phase-contrast CT (PB-CT) is a novel imaging technique that visualises variations in both X-ray attenuation and refraction. This study aimed to compare the clinical image quality of breast PB-CT using synchrotron radiation with ...
Lockie, Darren, Fox, J, Kumar, Beena, Kumar, B, Patrick Brennan, Peele, Andrew, Patrycja Baran, Brennan, Patrick C., Lewis, S, Fox, Jane, Thompson, D, Quiney, Harry M., Mayo, Sheridan C., Tromba, G, Prodanovic, Z, Zdenka Prodanovic, Timur Gureyev, Konstantin Pavlov, Andrew PEELE, Nesterets, YI, Yakov Nesterets, Harry Quiney, Hausermann, Daniel, Taba, ST, Dimmock, Matthew, Beena Kumar, Mayo, SC, Daniel HAUSERMANN, Darren Lockie, Dimmock, M, Nesterets, Yakov I., Quiney, HM, Hall, Christopher, Thompson, Darren, Arhatari, Benedicta D., Taba, Seyedamir Tavakoli, Hall, C, Chris Hall, Gureyev, Timur E., Maksimenko, A, Lockie, D, Sherry Mayo, Darren Thompson, Brennan, PC, Maksimenko, Anton, Baran, Patrycja M., Pavlov, KM, Hausermann, D, Tromba, Giuliana, Pavlov, Konstantin M., Gureyev, TE, Seyedamir Tavakoli Taba, Peele, A, Lewis, Sarah (R21243), Giuliana Tromba, Prodanovic, Zdenka, Benedicta Arhatari, Anton Maksimenko, Sarah Lewis, Baran, PM, Jane Fox, Arhatari, BD, Matthew Dimmock   +62 more
core   +1 more source

Dual-time point 18FDG-PET/CT imaging may be useful in assessing local recurrent disease in high grade bone and soft tissue sarcoma [PDF]

, 2016
BACKGROUND: Sarcomas comprise 1% of malignant tumors in adults but represent a significant diagnostic and therapeutic challenge. Molecular imaging with 18FDG PET/CT is a powerful modality in oncology.
Yordanova, Tsvetelina, Dancheva, Zhivka; St Marina University Hospital 1, Hr. Smirnenski, Blvd 9010 Varna, Bochev, Pavel, Chaushev, Borislav, Klisarova, Aneliya   +4 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Prenatal stress alters amygdala functional connectivity in preterm neonates

NeuroImage: Clinical, 2016
Exposure to prenatal and early-life stress results in alterations in neural connectivity and an increased risk for neuropsychiatric disorders. In particular, alterations in amygdala connectivity have emerged as a common effect across several recent ...
Dustin Scheinost, Soo Hyun Kwon, Cheryl Lacadie, Gordon Sze, Rajita Sinha, R. Todd Constable, Laura R. Ment   +6 more
doaj   +1 more source

PET and SPECT Imaging of Brain Neoplasia Mimics

, 2020
Several non-neoplastic processes, including infection, inflammation, demyelination, vasculitis, autoimmune disease, and post-treatment changes (radiation therapy or chemoradiation) can result in a mass-like, space-occupying lesion on conventional ...
Koontz, Nicholas A., Gray, Benjamin R., Tann, Mark, Agarwal, Atul   +3 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma

World Journal of Nuclear Medicine, 2021
18F-2-fluoro-2-deoxy-D-glucose ([18F]-FDG) positron emission tomography (PET) CT has proven useful in the evaluation of high-grade glioma and is also useful as a predictor of the degree of malignancy in newly diagnosed brain tumors.
Ram Kumar, Nitin Gupta, Rajeev Ranjan, Ritu Verma, Ethel Belho, Ishita Sen   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source