Results 31 to 40 of about 244,114 (309)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

CT scanning and reconstruction of coal samples: principle, method and application

Meitan xuebao
The internal microstructure of coal directly affects the mechanical properties and seepage properties of coal. It is the internal factor that induces coal and gas outburst, water damage, spontaneous combustion and other disasters. It is very important to
Cun ZHANG, Sheng JIA, Yongle WANG, Yixin ZHAO, Yanhong CHEN, Fangtian WANG   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Feasibility Study of Advanced Cardiovascular Screening in Middle-Aged Patients with Diabetes

Clinical Epidemiology, 2020
Jes Sanddal Lindholt,1 Jan Frystyk,2 Jesper Hallas,3 Lars Melholt Rasmussen,4 Axel Cosmus Pyndt Diederichsen5 1Elitary Research Centre of Individualised Medicine in Arterial Disease (CIMA), Department of Cardiothoracic and Vascular Surgery, Odense ...
Lindholt JS, Frystyk J, Hallas J, Rasmussen LM, Diederichsen ACP   +4 more
doaj  

Determining method of multiscale fractal dimension of red bed sandstone pores based on CT scanning

地质科技通报, 2022
The distribution of pore structure inside rock has fractal characteristics in statistical sense, the determination of itsfractal dimension is of great significance to characterize the distribution law of pore structure quantitatively and reveal various ...
Zihan Zhang, Wen Wei, Jie Zhang, Hongbiao Jia   +3 more
doaj   +1 more source

(Table 1) X-ray micro-CT scanning of planktic foraminiferal from sediment cores

, 2019
(Table 1) X-ray micro-CT scanning of planktic foraminiferal from sediment ...
Okazaki, Yusuke, Iwasaki, Shinya, Ikehara, Minoru, Yusuke Okazaki (8059778), Minoru Ikehara (7976327), Kimoto, Katsunori, Shinya Iwasaki (8059775), Katsunori Kimoto (6433073)   +7 more
core   +1 more source

Development of a deep-water carbonate ion concentration proxy based on preservation of planktonic foraminifera shells quantified by X-ray CT scanning

, 2023
The quantitative and objective characterization of dissolution intensity in fossil planktonic foraminiferal shells could be used to reconstruct past changes in bottom water carbonate ion concentration. Among proxies measuring the degree of dissolution of
Iwasaki, Shinya, Kucera, Michal, Kimoto, Katsunori   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Evolution rules of fissures in expansive soils under cyclic action of coupling wetting-drying and freeze-thaw

Yantu gongcheng xuebao, 2019
The occurrence and evolution of fissures are the significant characteristics of expansive soils under the action of various external factors. With regard to the deterioration of slopes of the canals of expansive soils in high and cold regions in the ...
CAI Zheng-yin , ZHU Xun , HUANG Ying-hao , ZHANG Chen
doaj   +1 more source