Results 201 to 210 of about 180,278 (321)

MiR‐221‐3p Attenuates IL‐33‐Induced Mast Cell Cytokine Expression by Targeting KIT

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mast cells (MCs) are involved in type 2 inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP), which depends on interleukin (IL)‐33 stimulation. MiR‐221 is reported to be an important regulator of MCs, and miR‐221‐3p can be expressed in CRSwNP. However, the role of miR‐221‐3p in CRSwNP is unclear. Methods Ethmoid tissues
Ruowu Liu   +11 more
wiley   +1 more source

Tissue‐resident CD69+CXCR6+ Natural Killer cells with exhausted phenotype accumulate in human non‐small cell lung cancer

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1993-2005, December 2022., 2022
This study identified a CD69+CXCR6+ tissue‐resident NK (trNK) subset specifically accumulated in the tumor microenvironment of human non‐small cell lung cancer patients. CD69+CXCR6+ trNK cells showed an immunomodulatory‐like and exhaustion phenotype, and secreted IFN‐γ and TNF‐α rapidly. Abstract Natural killer (NK) cells with tissue‐residency features
Xiaoke Chen   +10 more
wiley   +1 more source

Addition of metformin to anti-PD-1/PD-L1 drugs activates anti-tumor immune response in peripheral immune cells of NSCLC patients. [PDF]

open access: yesCell Death Dis
Amato L   +16 more
europepmc   +1 more source

369 Safety and pharmacodynamic activity of ATOR-1015, a CTLA-4 x OX40 bispecific antibody, in a phase 1 dose escalation study of patients with advanced solid malignancies

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Gustav Ullenhag   +9 more
doaj   +1 more source

Anti‐L‐selectin monoclonal antibody treatment in mice enhances tumor growth by preventing CTL sensitization in peripheral lymph nodes draining the tumor area [PDF]

open access: green, 1996
Antonio Rosato   +7 more
openalex   +1 more source

Exploring the co‐morbid relationship between Alzheimer's disease and lung cancer in the 5xFAD transgenic mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of inverse comorbidities of Alzheimer's disease and lung cancer. Abstract Background Alzheimer's disease (AD) and lung cancer are leading causes of mortality among the older population. Epidemiological evidence suggests an antagonistic relationship between them, whereby patients with AD exhibit a reduced risk of developing cancer and ...
Mingfeng Li   +11 more
wiley   +1 more source

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