Results 1 to 10 of about 10,638,486 (296)

Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis

open access: yesPediatric Neurology Briefs, 2002
The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussens encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
openaire   +5 more sources

Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1987
To investigate how cytotoxic T lymphocytes (CTL) avoid killing themselves when they destroy target cells, we compared 20 different cell lines as target cells, including several CTL cell lines, for their susceptibility to lysis by CTL. Variations in recognition of this diverse set of target cells was circumvented by attaching to all of them a monoclonal
D M, Kranz, H N, Eisen
openaire   +2 more sources

Dynamics of cytotoxic T–lymphocyte exhaustion [PDF]

open access: yesProceedings of the Royal Society of London. Series B: Biological Sciences, 1998
We examine simple mathematical models to investigate the circumstances under which the dynamics of cytotoxic T-lymphocyte (CTL) activation and differentiation may result in the loss of virus specific CD8+ cells, a process known as CTL exhaustion. We distinguish between two general classes of viruses: (i) viruses infecting cells that are not involved in
Wodarz, D, Klenerman, P, Nowak, M
openaire   +4 more sources

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO [PDF]

open access: yesThe Journal of Experimental Medicine, 1974
Mouse cytotoxic T lymphocytes (CTL) were generated in unidirectional mixed leukocyte cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 spleen cells as stimulating cells. Cytotoxicity was assayed on 51Cr-labeled P-815 (DBA/2) target cells, and the relative frequency of CTL in individual cell populations was ...
Macdonald, H R   +3 more
openaire   +4 more sources

Killing Mechanisms of Cytotoxic T Lymphocytes

open access: yesPhysiology, 1998
Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules. Death of target cells is characterized by either necrosis or apoptosis, depending on the killing mechanism used and on the metabolism of the target cell itself.
Groscurth P, Filgueira L
openaire   +3 more sources

Intravital Imaging of Cytotoxic T Lymphocytes

open access: yes, 2014
Intravital imaging approaches are proving to be essential to address new questions to better understand how the immune system operates. These approaches are especially valuable to characterize the complex organization of immune responses in vivo. Here, we examine how to take advantage of the cornea as a natural body window to apply noninvasive imaging ...
Gaetano, Faleo   +2 more
openaire   +3 more sources

cytotoxic T lymphocyte

open access: yes
Citation: 'cytotoxic T lymphocyte' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13072 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

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