Results 1 to 10 of about 11,464,920 (290)

Kinetics of Gag-Specific Cytotoxic T Lymphocyte Responses During the Clinical Course of HIV-1 Infection: A Longitudinal Analysis of Rapid Progressors and Long-Term Asymptomatics.

Journal of Experimental Medicine, 1995
Richard J Bende, C A van Baalen, F Miedema   +2 more
exaly  

Endothelial Injury Mediated by Cytotoxic T Lymphocytes and Loss of Microvessels in Chronic Graft Versus Host Disease

Lancet, The, 2002
Jordan S Pober, Dimitrios A Tsakiris, Alois Gratwohl   +2 more
exaly  

HLA Restricted Virus-Specific Cytotoxic T-Lymphocyte Responses to Live and Inactivated Influenza Vaccines.

Lancet, The, 1981
A H Rook, F A Ennis, G C Schild
exaly  

Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis

Pediatric Neurology Briefs, 2002
The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussen’s encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
doaj   +5 more sources

Healthy aging—would cytotoxic T lymphocytes stand out? [PDF]

Cell Death Discovery, 2023
Senescent cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders.
Tianyu Zhang, Jinjin Zhang, Shixuan Wang
doaj   +2 more sources

Cytotoxic Responses Mediated by NK Cells and Cytotoxic T Lymphocytes in Xenotransplantation [PDF]

Transplant International
Xenotransplantation represents a potential solution to the shortage of organs for transplantation. The recent advancements in porcine genetic modification have addressed hyperacute and acute vascular rejection; however, challenges persist with regard to ...
Viktoriia Galdina, Gisella L. Puga Yung, Jörg D. Seebach   +2 more
doaj   +2 more sources

Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. [PDF]

PLoS ONE, 2012
Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Chi Wang Ip, Antje Kroner, Janos Groh, Marianne Huber, Dennis Klein, Irene Spahn, Ricarda Diem, Sarah K Williams, Klaus-Armin Nave, Julia M Edgar, Rudolf Martini   +10 more
doaj   +2 more sources

Cytotoxic T lymphocytes in regional lymph nodes in colon cancer

Acta Biomedica Scientifica
Background. The study of the subpopulation composition of cytotoxic T lymphocytes and the expression of co-inhibitory proteins on their surface in regional lymph nodes is necessary for the development of new methods of targeted therapy for colorectal ...
V. V. Kryukova, V. L. Tsepelev, P. P. Tereshkov   +2 more
doaj   +2 more sources

Rapamycin improves Graves’ orbitopathy by suppressing CD4+ cytotoxic T lymphocytes [PDF]

JCI Insight, 2023
CD4+ cytotoxic T lymphocytes (CTLs) were recently implicated in immune-mediated inflammation and fibrosis progression of Graves’ orbitopathy (GO). However, little is known about therapeutic targeting of CD4+ CTLs.
Meng Zhang, Kelvin K.L. Chong, Zi-yi Chen, Hui Guo, Yu-feng Liu, Yong-yong Kang, Yang-jun Li, Ting-ting Shi, Kenneth K.H. Lai, Ming-qian He, Kai Ye, George J. Kahaly, Bing-yin Shi, Yue Wang   +13 more
doaj   +2 more sources

Killing Mechanisms of Cytotoxic T Lymphocytes

Physiology, 1998
Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules.
Peter Groscurth, Luis Filgueira, Groscurth P, Filgueira L   +3 more
core   +4 more sources