Results 31 to 40 of about 344,235 (293)

Natural Killer cells responsiveness to physical esercise: a brief review [PDF]

, 2013
Natural killer cells (NK) are a group of peripheral blood lymphocytes which display cytotoxic ac- tivity against a wide range of tumour cells. They are a consistent part of the inflammatory re- sponse that is activated when either internal or external ...
Concu A., CRISAFULLI, ANTONIO, Melis F, MILIA, RAFFAELE, TOCCO, FILIPPO   +4 more
core   +1 more source

Altered CD94/NKG2A and perforin expression reduce the cytotoxic activity in malignant pleural effusions [PDF]

, 2011
CD94/NKG2A is an inhibitory receptor expressed by NK cells and cytotoxic lymphocytes and, upon activation by HLA-E, downregulates the cytolytic activities of these cells thus representing a tumour immune escape mechanism.
Bellia, V., Di Sano, C., Ferraro, M., Gjomarkaj, M., Olivieri, D., Pace, E., Santagata, R., Spatafora, M., Tipa, A.   +8 more
core   +1 more source

Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema

Respiratory Research, 2007
Background It is generally accepted that emphysematous lungs are characterized by an increase in the numbers of neutrophils, macrophages, and CD8+ T lymphocytes, the lasts having increased cytotoxic activity.
Parent Julie, Morissette Mathieu C, Milot Julie   +2 more
doaj   +1 more source

Influence of the age and disease colorectal in immunity cutaneous pericolostomic [PDF]

, 2009
Objective: describe the immunological response in the dermal layer of the peri-colostomic region. Method: Forty-one patients with colostomies realized over eight weeks previously, were included. For the analysis of the immunocellular response in the peri-
Franco, Marcello Fabiano de, Martins, Marcos Roberto, Matos, Delcio, Saad, Sarhan Sydney, Salles, Valdemir José Alegre   +4 more
core   +4 more sources

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula, Braga, Sofia, Cabral, M. Guadalupe, Jacinto, António, Saraiva, Diana P.   +4 more
core   +2 more sources

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner.

PLoS Pathogens, 2020
Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8+ T cells and NK cells) control HCMV infection by releasing interferon-γ and ...
Liling Shan, Shuang Li, Jan Meeldijk, Bernadet Blijenberg, Astrid Hendriks, Karlijn J W M van Boxtel, Sara P H van den Berg, Ian J Groves, Martin Potts, Adriana Svrlanska, Thomas Stamminger, Mark R Wills, Niels Bovenschen   +12 more
doaj   +1 more source

Cytotoxic T lymphocytes in regional lymph nodes in colon cancer

Acta Biomedica Scientifica
Background. The study of the subpopulation composition of cytotoxic T lymphocytes and the expression of co-inhibitory proteins on their surface in regional lymph nodes is necessary for the development of new methods of targeted therapy for colorectal ...
V. V. Kryukova, V. L. Tsepelev, P. P. Tereshkov   +2 more
doaj   +1 more source

Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7

Frontiers in Immunology, 2019
Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse.
Praneeth Chitirala, Keerthana Ravichandran, Donatella Galgano, Marwa Sleiman, Elmar Krause, Yenan T. Bryceson, Jens Rettig   +6 more
doaj   +1 more source

State of the immune system in women using the “Provag” probiotic

Медицинская иммунология, 2020
Lactobacilli are  widely used  in clinical  practice as probiotics, biologically  active  additives  and probiotic products for functional nutrition.
V. A. Kozlov, A. G. Borisov, A. A. Savchenko, A. E. Kondakov, I. V. Kudryavtsev   +4 more
doaj   +1 more source

Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4

Frontiers in Immunology, 2021
Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke   +6 more
doaj   +1 more source