Results 31 to 40 of about 344,235 (297)
Frontiers in Immunology, 2022 miRNAs dictate relevant virus-host interactions, offering new avenues for interventions to achieve an HIV remission. We aimed to enhance HIV-specific cytotoxic responses—a hallmark of natural HIV control— by miRNA modulation in T cells.
Nadia Madrid-Elena +23 more
doaj +1 more source
Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema
Respiratory Research, 2007 Background It is generally accepted that emphysematous lungs are characterized by an increase in the numbers of neutrophils, macrophages, and CD8+ T lymphocytes, the lasts having increased cytotoxic activity.
Parent Julie +2 more
doaj +1 more source
Influence of the age and disease colorectal in immunity cutaneous pericolostomic [PDF]
, 2009 Objective: describe the immunological response in the dermal layer of the peri-colostomic region. Method: Forty-one patients with colostomies realized over eight weeks previously, were included. For the analysis of the immunocellular response in the peri-
Franco, Marcello Fabiano de +4 more
core +4 more sources
HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]
, 2018 Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula +4 more
core +2 more sources
PLoS Pathogens, 2020 Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8+ T cells and NK cells) control HCMV infection by releasing interferon-γ and ...
Liling Shan +12 more
doaj +1 more source
Cytotoxic T lymphocytes in regional lymph nodes in colon cancer
Acta Biomedica ScientificaBackground. The study of the subpopulation composition of cytotoxic T lymphocytes and the expression of co-inhibitory proteins on their surface in regional lymph nodes is necessary for the development of new methods of targeted therapy for colorectal ...
V. V. Kryukova +2 more
doaj +1 more source
Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7
Frontiers in Immunology, 2019 Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse.
Praneeth Chitirala +6 more
doaj +1 more source
State of the immune system in women using the “Provag” probiotic
Медицинская иммунология, 2020 Lactobacilli are widely used in clinical practice as probiotics, biologically active additives and probiotic products for functional nutrition.
V. A. Kozlov +4 more
doaj +1 more source
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4
Frontiers in Immunology, 2021 Although the human immune response to cancer is naturally potent, it can be severely disrupted as a result of an immunosuppressive tumor microenvironment.
Tobias Burkard +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source