Results 231 to 240 of about 436,571 (380)

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Nature Network Boston, 2018
Peng Jiang, Shengqing Gu, D. Pan, Jingxin Fu, A. Sahu, Xihao Hu, Ziyi Li, Nicole Traugh, Xia Bu, Bo Li, Bo Li, Jun Liu, G. Freeman, Myles A. Brown, K. Wucherpfennig, X. Liu   +15 more
semanticscholar   +1 more source

CTL self-defence [PDF]

Nature Reviews Molecular Cell Biology, 2002
openaire   +4 more sources

Autophagy‐Targeting Fe–Cu Nanozyme for Tumor Immune Microenvironment Remodeling and Image‐Guided Cancer Immunotherapy

Advanced Science, EarlyView.
In this study, a multifunctional iron‐copper metal–organic framework nanozyme platform co‐delivering chloroquine and perfluorohexane is engineered to circumvent tumor immune evasion by disrupting autophagic flux and restoring major histocompatibility complex class I presentation. This dual‐action nanoplatform orchestrates synergistic autophagy blockade
Li Yan, Chao Chen, Yu Liang, Xiaowan Huang, Jieying Qian, Hao Zhang, Li Zhang, Yingjia Li, Yunjiao Zhang   +8 more
wiley   +1 more source

Investigation of the optimal condition for the induction of Cytotoxic T Lymphocytes(CTL) and application of CTL to gynecologic malignancies.

, 1992
Hiroshi Tsuda, Naohiko Umesaki
openalex   +2 more sources

PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells.

International Immunology, 2009
Wenshi Wang, R. Lau, Daohai Yu, Weiwei Zhu, A. Korman, J. Weber   +5 more
semanticscholar   +1 more source

Mild Photothermal Bimetallic Mesoporous Nanozyme Triggers Immunogenic Cell Death and Immune Contexture Remodeling for Precision Hepatocellular Carcinoma Treatment

Advanced Science, EarlyView.
In this study, a Pt/Co BNzyme with peroxidase/GPx‐like activity is developed, increasing oxidative stress by generating ROS and depleting GSH to induce ICD. The mild PTT effect enhanced its enzymatic activity. The Pt/Co BNzyme remodeled the TME, promoting DC maturation.
Yanbing Huang, Lei Ding, Yanbing Cao, Qiang Feng, Yanjuan Li, Jianmin Wang, Zhixiong Cai, Fuli Xin, Peiyuan Wang, Jingfeng Liu   +9 more
wiley   +1 more source

Targeting triple-negative breast cancer using cord-blood CD34⁺ HSPC-derived mesothelin-specific CAR-NKT cells with potent antitumor activity. [PDF]

J Hematol Oncol
Li YR, Shen X, Zhu Y, Li Z, Hon R, Tian Y, Huang J, Zhao AS, Ma NY, Zhang C, Lin D, Sargsyan K, Yuan Y, Yang L.   +13 more
europepmc   +1 more source

アデノウイルスベクターによるCD 80遺伝子導入腫瘍細胞を用いたCTLの誘導

, 1994

openalex   +2 more sources

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. [PDF]

, 1996
Rudolf Schmits, Thomas M. Kündig, D. Baker, G Shumaker, John Simard, G S Duncan, Andrew Wakeham, Arda Shahinian, A. van der Heiden, Martin F. Bachmann, Pamela S. Ohashi, Tak W. Mak, DD Hickstein   +12 more
openalex   +1 more source

Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy.

Cancer Research, 2010
T. Takeshima, K. Chamoto, D. Wakita, T. Ohkuri, Y. Togashi, H. Shirato, H. Kitamura, T. Nishimura   +7 more
semanticscholar   +1 more source