The transcriptional regulator CtrA controls gene expression in Alphaproteobacteria phages: Evidence for a lytic deferment pathway [PDF]
Frontiers in Microbiology, 2022 Pilitropic and flagellotropic phages adsorb to bacterial pili and flagella. These phages have long been used to investigate multiple aspects of bacterial physiology, such as the cell cycle control in the Caulobacterales. Targeting cellular appendages for
Satish Adhikari +2 more
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Connection Between Chromosomal Location and Function of CtrA Phosphorelay Genes in Alphaproteobacteria [PDF]
Frontiers in Microbiology, 2021 Most bacterial chromosomes are circular, with replication starting at one origin (ori) and proceeding on both replichores toward the terminus (ter). Several studies have shown that the location of genes relative to ori and ter can have profound effects ...
Jürgen Tomasch +2 more
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Trauma writing reduces conserved transcriptional response to adversity (CTRA) gene expression: A culturally adapted pilot study [PDF]
Comprehensive PsychoneuroendocrinologyIntroduction: Psychosocial interventions to reduce posttraumatic stress disorder (PTSD)-associated distress can improve health of people with PTSD. To identify potential biological mechanisms, we tested whether a PTSD-focused written emotional disclosure
Maria Di BelloMaria +2 more
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Pst and Tat Systems Are Essential for <i>Ehrlichia chaffeensis</i> Intracellular Survival and Regulated by CtrA. [PDF]
MicroorganismsEhrlichia chaffeensis is an obligate intracellular Gram-negative bacterium that infects human monocytes and macrophages, causing human monocytic ehrlichiosis (HME). HME is an emerging and highly threatening tick-borne infectious disease.
Zhou Y +8 more
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Frontiers in Cellular and Infection Microbiology, 2022 Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), is a Gram-negative obligatory intracellular bacterium, which infects and multiplies in human monocytes and macrophages.
Weihui Wu, Fang Bai, Yongxin Jin
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Diagnostic accuracy of Mirels score, CT-based Structural Rigidity Analysis, and Finite Element Analysis for predicting impending femoral pathologic fractures in metastatic bone disease: a systematic review. [PDF]
J Bone OncolBackground: Patients with metastatic bone disease affecting the femur are at substantial risk of pathologic fracture, resulting in significant morbidity and frequently necessitating urgent surgical intervention.
Salaja B, Lee M, O'Toole G, Molloy A.
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Neighborhood deprivation, breast cancer outcomes and stress-related gene expression in leukocytes and tumor tissue. [PDF]
Breast Cancer ResBackground Neighborhood socioeconomic deprivation is a recognized contributor to disparities in breast cancer outcomes, yet the biological mechanisms linking neighborhood context to tumor behavior remain poorly defined.
Shen J +4 more
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The paradox of action: Trajectories in distress, meaning, and gene regulation following self-directed activist engagement among Black women. [PDF]
SSM Ment HealthBackground: Black women have a long history of engaging in activism and community advocacy as both a political imperative and a survival strategy (Hill Collins, 2000; Ransby, 2003).
Geyton TA, Cole SW.
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MicrobiologyOpenCereibacter sphaeroides has a quorum sensing (QS) system that has been partially characterized. Using a bioinformatic approach, six LuxR homologs and one homolog of the acylhomoserine lactone synthase were identified in this bacterium, including the ...
Sebastian Poggio, Laura Camarena
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Lifestyle-dependent evolution and CtrA-mediated lifestyle transitions shape phage resistance in marine Roseobacter. [PDF]
Nat CommunMarine bacteria alternate between planktonic and surface-attached lifestyles, facing continuous phage predation. However, how these lifestyles shape resistance evolution remains poorly understood.
Li C +8 more
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