Cell Cycle Control by the Master Regulator CtrA in Sinorhizobium meliloti. [PDF]
PLoS Genetics, 2015 In all domains of life, proper regulation of the cell cycle is critical to coordinate genome replication, segregation and cell division. In some groups of bacteria, e.g.
Francesco Pini +10 more
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Integrative and quantitative view of the CtrA regulatory network in a stalked budding bacterium.
PLoS Genetics, 2020 The Alphaproteobacteria show a remarkable diversity of cell cycle-dependent developmental patterns, which are governed by the conserved CtrA pathway.
Oliver Leicht +6 more
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Architecture of divergent flagellar promoters controlled by CtrA in Rhodobacter sphaeroides
BMC Microbiology, 2018 Background Rhodobacter sphaeroides has two sets of flagellar genes, fla1 and fla2, that are responsible for the synthesis of two different flagellar structures. The expression of the fla2 genes is under control of CtrA.
Anet Rivera-Osorio +4 more
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Microorganisms, 2020 Bacteria employ regulatory networks to detect environmental signals and respond appropriately, often by adjusting gene expression. Some regulatory networks influence many genes, and many genes are affected by multiple regulatory networks.
Sonja Koppenhöfer, Andrew S. Lang
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Parasympathetic nervous activity and CTRA gene expression among healthy young adults in Japan. [PDF]
Brain Behav Immun HealthPrevious research suggests that parasympathetic nervous system (PNS) activity may inhibit the leukocyte Conserved Transcriptional Response to Adversity (CTRA) which has been observed in individuals exposed to prolonged stressors like loneliness, social ...
Murakami Y, Hashimoto T, Cole S.
europepmc +2 more sources
Comparison of distal and conventional transradial access on procedure duration and radiation exposure in carotid artery stenting. [PDF]
BMC Cardiovasc DisordObjective This study aimed to assess the effects of distal transradial access (dTRA) compared to conventional transradial access (cTRA) on procedure duration and radiation exposure among patients undergoing carotid artery stenting.
Wang LF +5 more
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Preoperative red cell width distribution to albumin ratio predicts early radial artery occlusion following coronary intervention via conventional transradial access. [PDF]
Sci RepThe red cell width distribution to albumin ratio (RAR) has recently been linked to various cardiovascular diseases. Radial artery occlusion (RAO) is a critical complication in patients undergoing coronary angiograph or percutaneous coronary intervention (
Song Y, Li W, Xiao J, Cai G.
europepmc +2 more sources
From Energy Deprivation Stress to Catalytic Adaptation of Reductive Dehalogenase TmrA for 1,1-DCA Dechlorination: An Experimental and in Silico Study. [PDF]
Microb BiotechnolAdaptive evolution of Dehalobacter restrictus strain UNSWDHB under a ratio of 1:9 chloroform:1,1‐DCA regime increased 1,1‐DCA dechlorination. Sequencing and molecular dynamics simulation reveal high‐entropy tmrA mutations that improved 1,1‐DCA binding energy and stabilize the catalytic pocket, outlining a route to tune reductive dehalogenases for ...
Ren Y, Landers E, Lee M, Manefield M.
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Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle
iScience, 2021 Summary: In the alphaproteobacterium, Caulobacter crescentus, phosphorylated CtrA (CtrA∼P), a master regulatory protein, binds directly to the chromosome origin (Cori) to inhibit DNA replication. Using a mathematical model of CtrA binding at Cori site [d]
Bronson R. Weston +2 more
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Psychological well-being and the human conserved transcriptional response to adversity. [PDF]
PLoS ONE, 2015 Research in human social genomics has identified a conserved transcriptional response to adversity (CTRA) characterized by up-regulated expression of pro-inflammatory genes and down-regulated expression of Type I interferon- and antibody-related genes ...
Barbara L Fredrickson +6 more
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