Results 71 to 80 of about 148,159 (359)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
nevenjovanovic/cts-croala 1.2.4
, 2017 Convert Neo-Latin XML editions from CroALa to CTS / CITE ...
Neven Jovanović, arsimr16, Alex Simrell
core +1 more source
Impact of climate and analysis of desertification processes in semi arid land in Algeria: using data of Alsat-1 and Landsat [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015 The degradation of natural resources in arid and semi-arid areas was highlighted dramatically during this century due to population growth and transformation of land use systems.
Z. Ahmed +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Um estudo sobre a educação em ciência, tecnologia e sociedade - CTS nas ciências naturais das séries iniciais do ensino fundamental no contexto da proposta curricular da Santa Catarina - PC/SC [PDF]
, 2009 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Educação Científica e Tecnológica, Florianópolis, 2009Nesta pesquisa analiso os documentos da Proposta Curricular de Santa Catarina - PC/SC - no âmbito das ...
Messores, Claudia Maria
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
CTS no ensino de engenharia: contribuições da Rede Engenharia, Tecnologia e Sociedade
, 2022 Based on the teaching experience of the Engineering, Technology and Society Network, this paper analyzes the contributions made by STS studies to engineering education.
Jiménez Becerra, Javier +1 more
core
Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2006 La discusión se basa en dos líneas argumentativas, respectivamente la caracterización de la noción de éter en las teorías preexistentes a las primeras mediciones interferométricas de Michelson como un término teórico ad hoc, preservado en la ...
A. Drewes, H. Palma
doaj