Results 121 to 130 of about 28,046 (256)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

CTV Guidance for Head and Neck Cancers [PDF]

International Journal of Radiation Oncology*Biology*Physics, 2018
Beth M, Beadle, Carryn M, Anderson
openaire   +2 more sources

Genetic Transformation Of Citrus Sinensis With Citrus Tristeza Virus (ctv) Derived Sequences And Reaction Of Transgenic Lines To Ctv Infection

, 2015
Transgenic Citrus sinensis (L.) Osb. plants, cvs. Valencia and Hamlin, expressing Citrus tristeza virus (CTV) derived sequences were obtained by genetic transformation. The gene constructs were pCTV-CP containing the 25 kDa major capsid protein gene (CTV-
Stach-Machado D.R., Rezende J.A.M., Mourao Filho F.A.A., Stipp L.C.L., Mendes B.M.J., Freitas Jr. W., Muniz F.R., Schinor E., Harakava R., De Souza A.J.   +9 more
core   +1 more source

Safety and Tolerability of Different Total Neoadjuvant Therapies in Patients With Locally Advanced Rectal Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Total neoadjuvant therapy (TNT) is the standard treatment for locally advanced rectal cancer (LARC). Few studies have focused on the toxicity of TNT. Moreover, the differences in safety and tolerability between radiotherapy‐first and chemotherapy‐first strategies remain unclear.
Shohei Udagawa, Hiroki Osumi, Senzo Taguchi, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Tomohiro Yamaguchi, Shota Fukuoka, Koichiro Yoshino, Keitaro Shimozaki, Takeru Wakatsuki, Mariko Ogura, Akira Ooki, Keisho Chin, Kensei Yamaguchi, Takashi Akiyoshi, Eiji Shinozaki   +17 more
wiley   +1 more source

MRI guided online adaptive radiotherapy and the dosimetric impact of inter- and intrafractional motion in patients with cervical cancer

Clinical and Translational Radiation Oncology
Purpose: The aim of this study was to evaluate the inter- and intrafractional organs motions and dosimetric advantages of MRI guided online adaptive radiotherapy for cervical cancer.
Shouliang Ding, Zun Piao, Meining Chen, Fanghua Li, Yongbao Li, Biaoshui Liu, Hongdong Liu, Xiaoyan Huang, Junyun Li   +8 more
doaj   +1 more source

Results of the objective analysis of two different CTV protocols.

, 2016
Results of the objective analysis of two different CTV protocols.
Jeong Geun Yi (3134796), Inyoung Song (3134799), Sung Min Ko (3134793), Jeong Hee Park (3134790)   +3 more
core   +1 more source

Identification of T:B Cell Multimers After Bispecific T Cell Engagement, Using Both Conventional and Imaging Flow Cytometry

Cytometry Part A, Volume 109, Issue 6, Page 425-435, June 2026.
ABSTRACT Bispecific T cell engagers bring together T cells with malignant B cell targets to enable synapse formation and disease eradication of hematological malignancies. The proportion of T cells and their ability to bind to their targets varies between patients and may be a biomarker of response.
Joanne E. Davis, Mandy Ludford‐Menting, Helena Peng, Darryl N. Johnson, David S. Ritchie, Rachel Koldej   +5 more
wiley   +1 more source

Tuning the Affinity of Chimeric Antigen Receptors Enhances the Function of Human Engineered Regulatory T Cells

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Affinity tuning of anti‐HLA‐A2 CARs reveals that lower‐affinity CAR‐Tregs exhibit reduced avidity and enhanced serial engagement, leading to increased activation and trogocytosis. These properties promote improved tissue infiltration, persistence, and survival in vivo, demonstrating that optimizing receptor–antigen dynamics enhances the therapeutic ...
Ada Sera Kurt, Marwa Elgosbi, Elisavet Kodela, Emmanuelle Landmann, Paula Ruiz, Yoh Zen, Jorge Torres‐Yaguana, Alexander Puttick, Quisha Bustamante, Minahil Sharjeel, Hannan Murshid, Marc Martinez‐Llordella, Alberto Sanchez‐Fueyo   +12 more
wiley   +1 more source

Peters featured on CTV News (Canada)

, 2022
Associate Professor Jonathan Peters was featured on CTV News (Canada) regarding information leaks at the U.S. Supreme Court. The segment titled U.S. Abortion Battle Heats Up aired 5/5/22.
Communications and Public Relations, Office of
core  

Toward universal dose prediction: A multi‐scale, multi‐objective framework for sequential boost radiotherapy

Medical Physics, Volume 53, Issue 6, June 2026.
Abstract Background Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occur primarily in the initial plan, the boost plan(s), or all plans, resulting in a time‐intensive, iterative optimization process.
Austen Matthew Maniscalco, Xinran Zhong, Sean Domal, Yu‐Chen Lin, David Sher, Mu‐Han Lin, Steve Jiang, Dan Nguyen   +7 more
wiley   +1 more source