Results 31 to 40 of about 1,613,911 (283)

Cu-based metalorganic systems: an ab initio study of the electronic structure

, 2007
Within a first principles framework, we study the electronic structure of the recently synthesized polymeric coordination compound Cu(II)-2,5-bis(pyrazol-1-yl)-1,4-dihydroxybenzene (CuCCP), which has been suggested to be a good realization of a ...
Buchsbaum, Christian, Jeschke, Harald O., Rahaman, Badiur, Saha-Dasgupta, Tanusri, Salguero, L. Andrea, Schmidt, Martin U., Valenti, Roser   +6 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Crystal structure and electronic structure of quaternary semiconductors Cu$_2$ZnTiSe$_4$ and Cu$_2$ZnTiS$_4$ for solar cell absorber

, 2012
We design two new I2-II-IV-VI4 quaternary semiconductors Cu$_2$ZnTiSe$_4$ and Cu$_2$ZnTiS$_4$, and systematically study the crystal and electronic structure by employing first-principles electronic structure calculations.
Blaha P., Junjie Li, Sumei Huang, Wenhui Xie, Xiaofeng Wang, Zhenjie Zhao   +5 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Pathogenesis and advances in immunotherapy for type 1 diabetes treatment

Biotechnology Reports
Type 1 diabetes (T1D) is an autoimmune disease marked by selective destruction of pancreatic β-cells, resulting in absolute insulin deficiency. Although insulin replacement remains the standard therapy, it does not address the underlying autoimmune ...
Tran Chi Linh, Nguyen Khanh Dung
doaj   +1 more source

Flow Rate and Interference Studies for Copper Binding to a Silica-Immobilized Humin Polymer Matrix: Column and Batch Experiments

Bioinorganic Chemistry and Applications, 2005
Batch and column experiments were performed to determine the Cu(II) binding capacity of silica-immobilized humin biomass. For column studies, 500 bed volumes of a 0.1 mM Cu(II) solution were passed through humin packed columns at the flow rates of 1, 1.5,
Jorge L. Gardea-Torresdey, Carolina Contreras, Guadalupe de la Rosa, Jose R. Peralta-Videa   +3 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Toxicity of copper (II) metal complexes with amino acids ligands: A study of activity in Aedes aegypti larvae [PDF]

Anais da Academia Brasileira de Ciências
The larval control of Aedes aegypti has been done mainly by insecticides, which cause resistance and environmental contamination and have a high-cost development and application.
EDUARDO JOSÉ DE ARRUDA, CÍCERA MARIA DA SILVA, ALESSANDRA R. LIMA, GLENDA B. PORZANI, MONIZE M. DA SILVA, CLÁUDIO T. DE CARVALHO, ISAÍAS CABRINI, MAGDA F. FERNANDES   +7 more
doaj   +1 more source

Interplay between structure and magnetism in the low-dimensional spin system $K(C_8H_{16}O_4)_2CuCl_3{*}H_2O$

, 2017
Materials based on a crown ether complex together with magnetic ions, especially Cu(II), can be used to synthesize new low dimesional quantum spin systems. We have prepared the new crown ether complex Di-\mu-chloro-bis(12-crown-4)-aquqdichloro-copper(II)-
Assmus, Wolf, Bolte, Michael, Delley, Bernard, Krellner, Cornelius, Lang, Michael, Rüegg, Christian, Schefer, Jürg, van Well, Natalija, Wolf, Bernd   +8 more
core   +1 more source