Results 11 to 20 of about 3,862 (154)

Studying When to Add Biological Therapy to Cytotoxic Therapy in Advanced Cancer Care Using Real World Data: How to Avoid Design Choices That Generate Immortal Time. [PDF]

Cancer Med
ABSTRACT Background Since real‐world data lack information on treatment assignment (usually the only information available is treatment prescription/administration) and early outcomes can happen in advanced cancer, some design choices may introduce immortal time due to selection or due to treatment strategy misclassification.
Garcia-Albeniz X, Vila-Guilera J, Zamparini M, Oliveres H, Alonso-Orduna V, Feliu J, Fernández-Montes A, Martín-Richard M, Gálvez-Munoz E, Ruiz-Casado A, Yubero-Esteban A, Aparicio J, Alcaide-Garcia J, Plazas JG, Fernandez-Martos C, Gallego-Sanchez R, Morales MG, Leno R, Esposito F, Lopez-Prades S, Cuatrecasas M, Dickerman BA, Maurel J.   +22 more
europepmc   +2 more sources

The OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus. [PDF]

Histopathology
The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.
Delgado Guillena PG, Cuatrecasas M, Montori S, Felipez Varela N, Llach J, Archilla I, Florez-Diez P, Barreiro-Alonso E, Tejedor-Tejada J, Vicente R, Soria MT, Huerta A, Ortega SP, Nuñez H, Patrón O, Mangas C, Zaffalon D, Hernández L, Yip LE, Hontoria G, Hijos G, Domper-Arnal MJ, Zarraquiños S, Herreros De Tejada A, Córdoba A, Cuestas A, Fernández-Esparrach G, Moreira L, Albéniz E, EpiGASTRIC/EDGAR Consortium.   +29 more
europepmc   +2 more sources

Interobserver variability of histopathological assessment in pT1 colorectal carcinoma. [PDF]

Histopathology
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
de Gordoa KS, Daca-Alvarez M, Rodrigo-Calvo M, Archilla I, Lopez-Prades S, Aguirre JJ, Alarcón-Molero L, Jurado MC, Canosa A, Giner F, González-Lois C, Jimeno M, Jurado I, Machado I, Martínez-Ciarpaglini C, Musulen E, Naranjo D, Papaleo N, Peña C, Rosiñol Ò, Sánchez-Yuste R, Benítez GTV, Pellisé M, Cuatrecasas M, EpiT1 Consortium.   +24 more
europepmc   +2 more sources

Josep Cuatrecasas i Arumí: notes per a una biografia

Collectanea Botanica, 1997
Peer ...
Josep M. Montserrat i Marti
doaj   +3 more sources

Are We Witnessing a Speciation Continuum? Evidence From Current and Past Gene Flow in the Genus Oritrophium s.s. (Asteraceae) From the Tropical High Andes. [PDF]

Mol Ecol
ABSTRACT Determining species boundaries is key for appropriately assessing biodiversity. However, the continuity of the speciation process makes delimiting species a difficult task, especially for recently diverged taxa. Furthermore, past introgression may leave traces that result in reticulate evolutionary patterns, challenging the estimation of ...
Gorospe JM, Salomón L, Armijos-Barros J, Kantor A, Kolář F, Arnelas I, Sklenář P, Schmickl R.   +7 more
europepmc   +2 more sources

¿Por qué las partes pactarían un ROFR? Profundizando en el right of first refusal

Thēmis, 2023
El presente artículo tiene como objetivo que el lector conozca las principales instituciones y características del derecho de primera opción (conocido como ‘right of first refusal’ en la doctrina anglosajona) instaurado en un convenio de accionistas, y, 
Diego Carrión Alvarez Calderón
doaj   +1 more source

Determinación del sexo en borojó (Borojoa patinoi, Cuatrecasas) mediante marcadores moleculares

Revista Colombiana de Biotecnología, 2004
El borojó (Borojoa patinoi, Cuatrecasas) una rubiacea endémica de la región Pacífica de Colombia, produce un fruto carnoso con importantes propiedades alimenticias que lo posicionan como un recurso genético promisorio.
Clara Inés Giraldo, Lucero Rengifo, Enrique Aguilar, Álvaro H. Alegría   +3 more
doaj   +2 more sources

Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome. [PDF]

Int J Cancer
What's new? Serrated polyposis syndrome has been associated with an increased risk of colorectal cancer. HIC1 is a tumor suppressor gene commonly silenced in serrated polyps and several cancers. This study suggests HIC1 as a novel germline predisposition factor to serrated polyposis syndrome, with variants altering gene transcriptional regulation and ...
Domínguez-Rovira X, Arnau-Collell C, Gonfaus-Ortiz G, Llargués-Sistac G, Muñoz J, Llopis A, Soares de Lima Y, Herrera-Pariente C, Moreira L, Ocaña T, Díaz-Gay M, Cuatrecasas M, Carballal S, López-Novo A, Fernàndez G, Castells A, Bujanda L, Capellà G, Cubiella J, Rodríguez-Alcalde D, Valle L, Balaguer F, Ruiz-Ponte C, Bonjoch L, Castellví-Bel S.   +24 more
europepmc   +2 more sources

Polymorphic Single-Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta-Analysis, Thakkinstian's Algorithm and FPRP Criterium. [PDF]

Cancer Med
ABSTRACT Background Considerable epidemiological studies have examined the correlation between polymorphic single‐nucleotide variants (SNPs) in miRNA genes and colorectal carcinoma (CRC) risk, yielding inconsistent results. Herein, we sought to systematically investigate the association between miRNA‐SNPs and CRC susceptibility by combined evaluation ...
Liu Q, Archilla I, Lopez-Prades S, Torres F, Camps J, Cuatrecasas M.   +5 more
europepmc   +2 more sources

RNA-sequencing: A reliable tool to unveil transcriptional landscape of paediatric B-other acute lymphoblastic leukaemia. [PDF]

Br J Haematol
Using current standard‐of‐care tests used in clinical practice, 20%–30% of B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) patients remain unclassified. These patients are grouped into a heterogeneous category named B‐other ALL and are all treated with the same intensity. The application of RNA‐seq, together with the integration of standard‐of‐
Vicente-Garcés C, Fernández G, Esperanza-Cebollada E, Richarte-Franqués M, Crespo-Carrasco A, Montesdeoca S, Isola I, Sarrate E, Cuatrecasas E, Rives S, Dapena JL, Camós M, Vega-García N.   +12 more
europepmc   +2 more sources