Results 21 to 30 of about 21,569 (221)

The OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus. [PDF]

open access: yesHistopathology
The new OLGIMA method for histological gastric cancer risk assessment is based on the severity of glandular atrophy and intestinal metaplasia, in both antrum and corpus, according to the Updated Sydney classification. The highest score of either atrophy or intestinal metaplasia from each location will be used for the final OLGIMA stage.
Delgado Guillena PG   +29 more
europepmc   +2 more sources

Interobserver variability of histopathological assessment in pT1 colorectal carcinoma. [PDF]

open access: yesHistopathology
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
de Gordoa KS   +24 more
europepmc   +2 more sources

Are We Witnessing a Speciation Continuum? Evidence From Current and Past Gene Flow in the Genus Oritrophium s.s. (Asteraceae) From the Tropical High Andes. [PDF]

open access: yesMol Ecol
ABSTRACT Determining species boundaries is key for appropriately assessing biodiversity. However, the continuity of the speciation process makes delimiting species a difficult task, especially for recently diverged taxa. Furthermore, past introgression may leave traces that result in reticulate evolutionary patterns, challenging the estimation of ...
Gorospe JM   +7 more
europepmc   +2 more sources

¿Por qué las partes pactarían un ROFR? Profundizando en el right of first refusal

open access: yesThēmis, 2023
El presente artículo tiene como objetivo que el lector conozca las principales instituciones y características del derecho de primera opción (conocido como ‘right of first refusal’ en la doctrina anglosajona) instaurado en un convenio de accionistas, y, 
Diego Carrión Alvarez Calderón
doaj   +1 more source

Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome. [PDF]

open access: yesInt J Cancer
What's new? Serrated polyposis syndrome has been associated with an increased risk of colorectal cancer. HIC1 is a tumor suppressor gene commonly silenced in serrated polyps and several cancers. This study suggests HIC1 as a novel germline predisposition factor to serrated polyposis syndrome, with variants altering gene transcriptional regulation and ...
Domínguez-Rovira X   +24 more
europepmc   +2 more sources

RNA-sequencing: A reliable tool to unveil transcriptional landscape of paediatric B-other acute lymphoblastic leukaemia. [PDF]

open access: yesBr J Haematol
Using current standard‐of‐care tests used in clinical practice, 20%–30% of B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) patients remain unclassified. These patients are grouped into a heterogeneous category named B‐other ALL and are all treated with the same intensity. The application of RNA‐seq, together with the integration of standard‐of‐
Vicente-Garcés C   +12 more
europepmc   +2 more sources

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