Results 171 to 180 of about 53,902 (261)

Risk Prediction of Early‐Onset Hepatocellular Carcinoma: Derivation and Validation in a Nationwide Young Adult Cohort

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 1,756,593 young adults, a generalized boosted survival model predicted incident HCC with strong discrimination (1‐year AUROC 0.945; 5‐year 0.825). The 1‐year horizon uniquely targets an imaging‐silent, pre‐diagnosis window, showing routine clinical signals can flag otherwise undetectable risk.
Seogsong Jeong   +7 more
wiley   +1 more source

Prevalence and Burden of Fatigue Across Disorders of Gut–Brain Interaction: Results From the Rome Foundation Global Epidemiology Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...
Fleur Veldman   +7 more
wiley   +1 more source

Impact of CD34+ cell dose on outcomes of related allogeneic PBSCT in adult AML patients

open access: yesBritish Journal of Haematology, EarlyView.
Summary CD34+ cell dose is believed to impact the outcomes of allogeneic peripheral blood stem cell transplantation (PBSCT), yet the optimal dose remains unclear. We retrospectively reviewed 2407 adult patients with acute myeloid leukaemia who underwent their first related PBSCT between 2000 and 2019.
Yusuke Toda   +21 more
wiley   +1 more source

Central nervous system involvement and relapse in adult acute lymphoblastic leukaemia—a population‐based analysis in 2007–2022

open access: yesBritish Journal of Haematology, EarlyView.
Summary Central nervous system (CNS) involvement and relapse remains a clinical challenge in the management of acute lymphoblastic leukaemia (ALL), and studies among adult ALL patients are scarce. We identified all adult ALL patients in Sweden between 2007 and 2022 (n = 838) from the population‐based ALL register and evaluated factors associated with ...
Erik Boberg   +7 more
wiley   +1 more source

Long‐term quality of life in patients with bladder cancer following radical cystectomy

open access: yesBJU International, Volume 135, Issue 4, Page 675-683, April 2025.
Objectives To investigate changes in quality of life (QoL) up to 8 years after radical cystectomy (RC) and compare QoL after RC with a gender‐ and age‐matched Dutch normative population. Furthermore, we aimed to identify patient characteristics associated with QoL and QoL trajectories after RC.
Emine Akdemir   +8 more
wiley   +1 more source

Taxonomic and functional diversity of benthic foraminifera as a promising proxy for tidewater glacier retreat

open access: yesBoreas, EarlyView.
Ice sheets and glaciers globally are losing mass at increasing rates, with the strongest changes occurring at tidewater glaciers. These are rapidly retreating and often transitioning to land‐terminating with implications for sea level change and ecosystem functioning.
Eleonora Fossile   +5 more
wiley   +1 more source

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