Results 181 to 190 of about 53,902 (261)

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah   +7 more
wiley   +1 more source

3D Character Reconstruction from Hand‐drawn Model Sheets

open access: yesComputer Graphics Forum, EarlyView.
Abstract Hand‐drawn model sheets are widely used in character design to define 3D shape and appearance through sparse multi‐view drawings. Reconstructing 3D characters from such sparse inputs has traditionally been challenging due to insufficient visual information.
Hyejeong Yoon   +3 more
wiley   +1 more source

Controllable Intrinsic Surface Pattern Generation Using Slime Mold Simulations

open access: yesComputer Graphics Forum, EarlyView.
Abstract Surface‐based pattern simulations have proven valuable for texture design and scientific visualization, but existing methods face several limitations. Most simulations either target a narrow range of pattern types (e.g. spots, branching) or support a broad range of patterns at the cost of time‐consuming parameter tuning.
Jeffrey Layton   +2 more
wiley   +1 more source

Basis Networks: Learning basis functions for free‐form triangulations

open access: yesComputer Graphics Forum, EarlyView.
Abstract We present a framework for learning compactly supported basis functions that define tangent continuous surfaces based on coarse irregular triangle meshes. The basis functions are represented as MLPs. Smoothness of the basis functions is achieved by using the values of Loop basis functions as the parameterization of the surface.
T. Djuren, M. Alexa
wiley   +1 more source

Register‐Efficient Linear‐Time Evaluation in the Bernstein Basis

open access: yesComputer Graphics Forum, EarlyView.
Abstract We investigate the evaluation of points and derivatives of Bézier curves and surfaces on modern architectures, focusing on performance and guided by numerical error bounds. While the de Casteljau algorithm remains the reference for numerical robustness, its linear working‐set size imposes substantial register pressure on GPUs.
Gábor Valasek, Anna Lili Horváth
wiley   +1 more source

Mixed Super‐Circles

open access: yesComputer Graphics Forum, EarlyView.
Abstract We introduce mixed super‐circles, a position‐curvature formulation of the original dynamic 2D super‐helix model. Compared to the latter, purely curvature‐based model – the so‐called chained formulation –, the mixed formulation that we propose here drastically reduces the algorithmic complexity of the solving scheme – from quadratic to quasi ...
Emile Hohnadel   +2 more
wiley   +1 more source

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