Results 111 to 120 of about 4,038,445 (259)

Cue Exposure Therapy for Addiction Disorders: A Review of Systematic Reviews

open access: yes, 2021
Mål: Avhengighetsforskningen går for tiden gjennom et paradigmeskifte ved inkluderingen av adferdsavhengighet under avhengighet som paraplybegrep. Forskning har dokumentert nevrobiologiske og erfaringsmessige likheter mellom ulike avhengighetslidelser.
openaire   +1 more source

Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim   +28 more
wiley   +1 more source

Cannabis cue exposure: a pilot study about extinction contexts

open access: yes, 2015
Empirical thesis.Bibliography: pages 85-103.1. Introduction -- 2. Methods -- 3. Results -- 4. Discussion.Cue-exposure therapy can reduce cravings elicited by conditioned cues such as drug paraphernalia.
Barnier, Ellise M
core  

Development and Initial Validation of a Rock Climbing Craving Questionnaire (RCCQ)

open access: yesFrontiers in Psychology, 2018
Conceptual similarities have been identified between experiences of extreme sports athletes and those with drug and behavioral addictions. Evidence suggests rock climbers experience craving and other withdrawal-like states when abstinent from their sport.
Gareth Roderique-Davies   +3 more
doaj   +1 more source

Modeling cue-exposure therapy for alcohol use disorder in rhesus monkeys: Effects of putative cognitive enhancers. [PDF]

open access: yesDrug Alcohol Depend, 2023
Pareek T   +6 more
europepmc   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

open access: yesAdvanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker   +7 more
wiley   +1 more source

Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction

open access: yesMolecular Brain
Animals adaptively regulate aversive memories in safe environments through extinction, a process central to exposure therapy for anxiety disorders.
Yuki Mochizuki   +3 more
doaj   +1 more source

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