Results 101 to 110 of about 363,289 (302)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Variation in the perception of an L2 contrast : a combined phonetic and phonological account [PDF]

, 2009
The present study argues that variation across listeners in the perception of a non-native contrast is due to two factors: the listener-specic weighting of auditory dimensions and the listener-specic construction of new segmental representations.
Hamann, Silke
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Spatiotemporal Dynamics and Future Projections of Carbon Use Efficiency on the Mongolian Plateau: A Remote Sensing and Machine Learning Approach

Remote Sensing
The Mongolian Plateau, a critical area for global climate change response, faces increasing vulnerability from climate change and human activities impacting its arid ecosystems. This study integrates GeoDetector and machine learning to predict vegetation
Xinyu Yang, Qiang Yu, Buyanbaatar Avirmed, Yu Wang, Jikai Zhao, Weijie Sun, Huanjia Cui, Bowen Chi, Ji Long   +8 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Changes in global carbon use efficiency in the 21st century and the potential controlling factors

Environmental Research Letters
Extensive studies have demonstrated the spatiotemporal changes in carbon use efficiency (CUE) and its driving factors over the past three decades. However, how the global CUE will change and to what extent the CUE is affected by the dominant factor in ...
Guo Chen, Tiantian Chen, Li Peng
doaj   +1 more source

Metacognition of visual short-term memory: Dissociation between objective and subjective components of VSTM

Frontiers in Psychology, 2013
The relationship between the objective accuracy of visual-short term memory (VSTM) representations and their subjective conscious experience is unknown.
Silvia eBona, Zaira eCattaneo, Zaira eCattaneo, Tomaso eVecchi, David eSoto, Juha eSilvanto   +5 more
doaj   +1 more source

Downright Sexy: Verticality, Implicit Power, and Perceived Physical Attractiveness

, 2009
Grounded theory proposes that abstract concepts (e.g., power) are represented by perceptions of vertical space (e.g., up is powerful; down is powerless).
Dionne, Sarah G., Meier, Brian P.
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source