Results 31 to 40 of about 3,300 (301)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

The role of terracotta figures and figurines in Mycenaean cult [PDF]

open access: yes, 2001
Since the time of Schliemann, Bronze Age scholars, while acknowledging the significance of figurines to Mycenaean cult, have not fully understood their function.
Richardson, Christine Mary
core  

A Hurrian-Mitanni Temple in Müslümantepe in The Upper Tigris and New Findings

open access: yesGaziantep Üniversitesi Sosyal Bilimler Dergisi, 2021
Conserning the Hurrian and Mitanni period, Muslumantepe appears to had been an ımportant center in the Upper Tigris region. What is particularly remarkable here is a palace structure from the Early Bronze Age surrounded by city walls. The temple from the
Eyyüp Ay
doaj   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

open access: yesAdvanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj   +8 more
wiley   +1 more source

The leader cult in communist Romania 1965-1989: constructing Ceaușescu's uniqueness in painting [PDF]

open access: yes, 2007
This study focuses on Ceaușescu’s cult in painting. Its aim is to demonstrate that in spite of obvious similarities with the master cult of Stalin, the Romanian leader's cult was not a simple adaptation of Stalin's cult, but it had its own ...
Mocanescu, Alice Carmen Rodica
core  

On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy

open access: yesAdvanced Science, EarlyView.
An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

open access: yesAdvanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang   +8 more
wiley   +1 more source

The role of saintly personalities in popular discourses from around 1970 on Baroque artistic cultures [PDF]

open access: yesJournal of Art Historiography, 2016
This article identifies a number of concepts that have been used in popular discourse on Baroque art, architecture and visual culture on both sides of the Iron Curtain.
Ivan Gerát
doaj  

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