Results 101 to 110 of about 538,969 (317)

Cultural Dimensions And CRM Systems: A Cross-Cultural Case Study’

open access: yes, 2006
Cultural dimensions are often identified as a crucial influence on the success or failure of Information Systems in general and Customer Relationship Management Systems (CRM) in particular.
Brooks, L, Ali, M, Alshawi, S
core  

Unpacking the Cultural DNA of Traditional Chinese Private Gardens Through Mathematical Measurement and Parametric Design

open access: yes, 2016
Traditional Chinese private gardens have unique cultural significance for the world’s architectural and landscape heritage. To compliment the existing qualitative understandings in the field, this chapter presents a computational approach to unpacking ...
Ostwald, Michael J.   +8 more
core   +1 more source

Addressing the Addressees: A Discourse Stylistic Study of the Vocatives in the Holy Qurʼān

open access: yesPakistan Journal of Islamic Research
This study investigates the function of vocatives in the Holy Qurʼān. The actual purpose of vocatives is to attract the attention of the addressee for a specific message, order, warning, command, instructions, awareness, and other exclamatory purposes ...
Sarwat Awan   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Use of Virtual Reflectance Transformation Imaging (V-RTI) in the Field of Cultural Heritage: Approaching the Materiality of an Ancient Egyptian Rock-Cut Chapel

open access: yesApplied Sciences
Recent progress in the realm of imaging technologies has swiftly disseminated fresh methodologies for representing objects, broadening the horizons for scholars such as art historians, archaeologists, conservators, and conservation scientists ...
Federico Di Iorio   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Cross-cultural analysis: methods and applications

open access: yes, 2018
Intended to bridge the gap between the latest methodological developments and cross-cultural research, this interdisciplinary resource presents the latest strategies for analyzing cross-cultural data.

core  

Cognitive–Cultural Balance in Designing Culture-Based HOTS Tasks: Evidence from Prospective Mathematics Teachers

open access: yesJurnal Kependidikan
This study aims to investigate how prospective mathematics teachers integrate cognitive and cultural dimensions in designing culture-based Higher Order Thinking Skills (HOTS) tasks.
Alifiani   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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