Results 111 to 120 of about 538,969 (317)

Cultural dimensions and CRM systems: a structurational analysis

open access: yes, 2008
Cultural dimensions are often identified as a crucial influence on the success or failure of Information Systems in general and Customer Relationship Management Systems (CRM) in particular.
Brooks, L, Ali, M, Alshawi, S
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Norwegian cultural policy: a civilising mission? [PDF]

open access: yes
This dissertation aims to explore the extent to which what has been termed „the civilising mission‟ has been a central rationale behind Norwegian cultural policy.
Bjørnsen, Egil
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Web-Based Knowledge Extraction and the Cognitive Characterization of Cultural Groups

open access: yes, 2011
The advent of Web 2.0 has provided new opportunities for cultural analysts to understand more about the cognitive characteristics of cultural groups. In particular, user-contributed content provides important indications as to the beliefs, attitudes and ...
Sieck, Winston R   +3 more
core  

Exploring cultural influences on employee interpretations of universal values messages in multinational organisations: a business discourse approach [PDF]

open access: yes, 2010
This thesis focuses on an increasingly popular, but little studied organisational communication practice, the deployment of corporate values messages as a means of ‘framing’ reality, and of achieving ‘shared meaning’ in multicultural workplaces, and ...
Lazidou, Domna
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Cultural Approach to the Management of the International Human Resource: An Analysis of Hofstede’s Cultural Dimensions

open access: yesInternational Journal of Business Administration, 2013
The subject of culture has gained much prominence and attention in the management of international human resource. This paper examines the issues of culture, both national and organisational, reviews and discusses relevant literature and draws conclusions based on the issues at hand.
openaire   +3 more sources

Newtonian-cultural motion method: a transdisciplinary method for migrant studies

open access: yesFrontiers in Sociology
This paper introduces a transdisciplinary methodological approach, the Newtonian-Cultural Motion Method (NCMM), which integrates Newton’s laws of motion with Williams’ cultural theory of dominant, residual, and emergent culture.
M. A. Pavithra, M. Subbulakshmi
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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