Results 61 to 70 of about 2,819,484 (256)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

AN INVESTIGATION ON THE INDONESIAN CULTURAL ASPECTS IN ENGLISH TEXTBOOKS FOR SENIOR HIGH SCHOOLPUBLISHED BY KEMENDIKBUD

Lingual, 2019
Cultural understanding is the core of language acquisition because language and culture can not be seperated with language. Culture can be understand through media either electronic or manual such internet, magazine, textbooks etc. Textbook is one of the
samsudin syam
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Cultural Aspects of Suicide

The Scientific World Journal, 2005
Undefined cultural factors cannot be dismissed and significantly contribute to the worldwide incidence of death by suicide. Culture is an all embracing term and defines the relationship of an individual to his environment. This study seeks to investigate
Hari D. Maharajh, Petal S. Abdool
doaj   +1 more source

Linking pattern to process in cultural evolution: explaining material culture diversity among the Northern Khanty of Northwest Siberia [PDF]

, 2009
Book description: This volume offers an integrative approach to the application of evolutionary theory in studies of cultural transmission and social evolution and reveals the enormous range of ways in which Darwinian ideas can lead to productive ...
Jordan, P.
core  

Agricultural Turns, Geographical Turns: Retrospect and Prospect. [PDF]

, 2004
It is accepted that British rural geography has actively engaged with the ‘cultural turn’, leading to a resurgence of research within the sub-discipline. However, a reading of recent reviews suggests that the cultural turn has largely, if not completely,
Arensberg, Atkins, Atkins, Barnett, Barnett, Bell, Bell, Bouquet, Bowler, Burgess, Burgess, Buttel, Buttel, Carol Morris, Carr, Clark, Clark, Cloke, Cloke, Cloke, Cook, Cook, Cook, Cook, Coppock, Crang, Eagleton, Emmett, Evans, Evans, Evans, Frankenberg, Gasson, Gerber, Gilg, Gillmor, Goodman, Goodman, Goodman, Gray, Gray, Harrison, Harrison, Harvey, Harvey, Holloway, Holloway, Holloway, Hughes, Ilbery, Ilbery, Ilbery, Jackson, Jackson, Johnson, Kloppenburg, Le Heron, Lee, Liepins, Liepins, Little, Littlejohn, Lowe, Lowe, Lowe, MacNaughton, Marsden, Marsden, Marsden, Marsden, Marsden, Marsden, Marsden, Marsden, McDowell, McEachern, McHenry, McMichael, Meinhof, Middleton, Milbourne, Morgan, Morris, Morris, Morris, Morris, Murdoch, Murdoch, Murdoch, Murdoch, Newby, Nick Evans, Pacione, Parrott, Phillips, Phillips, Phillips, Philo, Philo, Philo, Philo, Pile, Rapport, Ray, Rees, Rose, Seymour, Short, Strathern, Strathern, Thrift, Tsouvalis, Valentine, van der Ploeg, van der Ploeg, van Koppen, Vanclay, Wallace, Walsh, Walter, Whatmore, Whatmore, Whatmore, Whatmore, Whatmore, Williams, Williams, Wilson, Wolch, Woods, Wynne, Yarwood, Yarwood, Young   +133 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Traducción de referencias culturales en textos biomédicos sobre enfermedades neuromusculares (francés - español) [PDF]

Çédille: Revista de Estudios Franceses, 2015
Studies that focus on the translation of biomedical texts often do not address issues of cultural nature. However, references appear in these texts to specific aspects of the socio cultural context in which they are generated.
Elena Sánchez Trigo, Tamara Varela Vila
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