Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Implications of Cultural Background on Labour Market Choices: The Case of Religion and Entrepreneurship [PDF]
We suggest a methodology for identifying the implications of alternative cultural and social norms embodied by religious denomination on labour market outcomes, by estimating the differential impact of Protestantism versus Catholicism on the propensity ...
Nunziata, Luca, Rocco, Lorenzo
core
Cooperative Cross-Cultural Instruction: The Value of Multi-cultural Collaboration in the Coteaching of Topics of Worldview, Knowledge Traditions, and Epistemologies [PDF]
For four years (2011, 2013, 2014, 2015) two faculty members of the University of Alaska Fairbanks’ Center for Cross-cultural Studies have collaborated to co-teach a course entitled Traditional Ecological Knowledge (CCS 612).
Arevgaq, Theresa John, Koskey, Michael
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Female perception of risk with regard to cultural background [PDF]
Cross-cultural studies showed that cultures had influence on risk perceptions. The research presented here focused on the female perception of risk, since previous studies underline some gender difference.
Pergar Kuscer Marjanca +2 more
core +1 more source
Communication in cross-cultural consultations in primary care in Europe: the case for improvement. The rationale for the RESTORE FP 7 project [PDF]
The purpose of this paper is to substantiate the importance of research about barriers and levers to the implementation of supports for cross-cultural communication in primary care settings in Europe.
Burns, N. +10 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The identity representation of a Russian politician: a comparative analysis of two interviews [PDF]
The paper analyzes the interviews of two government officials – both ministers (of education and defence) at the time the interview was conducted – and how they (de)construct their institutional and professional identities in their discourses.
Irina Khoutyz
doaj
ENGLISH TEACHERS' CULTURAL BACKGROUND AND THEIR TEACHING BELIEF
This paper is a non-research article which aims at elaborating the relation between teachers’ cultural background and their teaching beliefs. Way of thinking, behaviour, value, tradition, and belief in a society are taken into account as aspects of ...
Heidy Wulandari
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source

