Results 71 to 80 of about 2,196,045 (307)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Iraj Poureslami,1,2 Susan Kwan,3 Stephen Lam,4,5 Nadia A Khan,6,7 John Mark FitzGerald 8,9 1Respiratory Division, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada; 2Department of Graduate ...
Poureslami I +4 more
doaj
Optimal educational choice and redistribution when cultural background matters [PDF]
Higher education plays an important role in determining lifetime earnings. In turn, the decision to become educated depends to a large extent on family characteristics, such as wealth and cultural background.
Elena Del Rey, Marìa del Mar Racionero
core
Early French views of the Waikato and its inhabitants (1840-54) [PDF]
This paper will investigate how the cultural background of these Frenchmen informed their descriptions of Waikato Maori and the Waikato environment. It will use the newly-published ten-volume collected correspondence of the pioneer Marists in the Pacific,
Jennings, William
core +1 more source
Irrelevant Cultural Influences on Belief [PDF]
Recent work in psychology on ‘cultural cognition’ suggests that our cultural background drives our attitudes towards a range of politically contentious issues in science such as global warming.
McKenna, Robin
core +2 more sources
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
More often than not, the assessment of literacy has focused upon how well readers attain various levels of reading comprehension or demonstrate proficiency with specific reading skills rather than reveal a readers cognitive abilities as reflected in ...
Lorraine Dagostino +4 more
doaj
Cultural and psychological background of society for implementation of English education at primary schools and the students’ capability in this regard [PDF]
The main purpose of this study was to survey the “cultural and psychological background of society” and “the students’ capability” to learn English” at elementary level of education. In this study, descriptive–survey method was used.
Mohammad Javad Liyaghatdar +2 more
doaj
The African-American Intellectual of the 1920s: Some Sociological Implications of the Harlem Renaissance [PDF]
This paper deals with some of the sociological implications of a major cultural high-water point in the African American experience, the New Negro/Harlem Renaissance.
Perry, Robert L., Peters, Melvin T.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

