Results 91 to 100 of about 129,793 (261)

Regression of CEO cultural background and firms’ overinvestment.

open access: yes, 2023
Regression of CEO cultural background and firms’ overinvestment.
Ya-Ling Huang (1602679)   +3 more
core   +1 more source

A Study on Animal Drugs in Khaqani’s Divan [PDF]

open access: yesمتن شناسی ادب فارسی, 2014
Difficulty and strangeness are the adjectives which have been ascribed to Khaqani’s Daivan for a long time. A notable part of such difficulties originates from the extensive cultural background on which the poet has based different themes, images and ...
S Mahdavifar
doaj  

The Inclusion of Cultural Diversity in Higher Education Curriculum Design

open access: yesInternational Journal of Contemporary Educational Research, 2018
This paper reports findings of a study which assesses the measures taken by universities in selected South East Asian countries when developing the competencies of students from other countries.
Shukran Abdul Rahman, Azlin Alwi
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Intergenerational Educational Mobility in the Comprehensive Danish Welfare State: Testing the Primacy of Non-monetary Social Origin Effects [PDF]

open access: yes
The aim of this paper is investigate the extent to which monetary and non-monetary social background factors explain intergenerational educational attainment in Denmark. The main hypothesis tested is that non-monetary social background factors (cultural,
Anders Holm, Mads Meier Jæger
core  

Cultural competency in the delivery of health services for Indigenous people [PDF]

open access: yes, 2015
Aim and objectives This review aims to examine available evidence on cultural competence in health care settings to identify key approaches and strategies that can contribute to improving the development and implementation of Indigenous health services ...
K Tsey (9849185)   +15 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Does cultural background affect volunteering behavior?

open access: yes, 2009
The purpose of this qualitative investigation is to help nonprofit organizations which rely heavily on the support of volunteers increase the effectiveness of their marketing by accounting for differences in cultural background among community members ...
Randle, Melanie, Dolnicar, Sara
core   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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