Results 141 to 150 of about 4,594,987 (303)

S'Esclop. Quadern cultural 2003, no. 8

, 2003
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Esclop Associació Cultural
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A cultural center in Pori

, 2019
This work is based on a competition for Pori cultural center Aarre launched in november 2018. Located in the historical city center, the chosen plot includes sensitive buildings from different eras such as Satakunta Museum and hotel Otava and complex urban relationships.
openaire   +1 more source

S'Esclop. Quadern cultural 2007, no. 31

, 2007
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Esclop Associació Cultural
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Integrated arts engagement as preventive infrastructure for active and healthy aging: a conceptual and policy framework. [PDF]

Front Public Health
Li F, Suo H, Chen S, Zhang C.
europepmc   +1 more source

S'Esclop. Quadern cultural 2002, no. 4

, 2002
not ...
Esclop Associació Cultural
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Challenges in implementing optimal perinatal regionalization: a scoping review. [PDF]

Matern Health Neonatol Perinatol
Heidarzadeh M, AbdollahiAbed L, Nakhaee M, Parnian E, Daemi A.   +4 more
europepmc   +1 more source

Gottsunda Culture center

, 2019
Stadsdelen Gottsunda har en bred variation i byggnader, både i storlek men även i stil. Den större södra delen består till största del av 1960-talets miljonprogram. Stadsdelen har en väldigt rik kultur som borde upplysas och tas vara på. Min första ingång i det här projektet var att med hjälp av arkitektur lyfta upp några av dem starka och positiva ...
openaire   +1 more source