Results 161 to 170 of about 4,594,987 (303)
Comment on "Adaptation Processes to Loneliness Among Older Adults: A Qualitative Study". [PDF]
Geriatr Gerontol IntHe K, Sui RL, Kong QZ, Wang JT, Sun ZG.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Sports, culture and tourism in cities along the Beijing-Hangzhou Grand Canal: sustainable development via SWOT analysis and point-axis spatial optimization. [PDF]
Front Sports Act LivingHongda T, Yonghu Z.
europepmc +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Clinical Blindness to Eating Disorders in Older Adults: A Qualitative Study of Primary Care Nurses' Perspectives. [PDF]
Healthcare (Basel)Muñoz-Ortega AV +5 more
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