Results 111 to 120 of about 14,438,745 (330)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Психологическая безопасность российских и китайских студентов, проживающих в общежитии

Научно-педагогическое обозрение
Статья посвящена изучению психологической безопасности в вузе. Исследование было проведено на выборке российских и китайских студентов, проживающих в общежитии. Были изучены структура и условия психологической безопасности.
Жданова Светлана Юрьевна, Краева Виктория Сергеевна   +1 more
doaj   +1 more source

Phylogenetic placements and cultural characteristics of Tuber species isolated from ectomycorrhizas. [PDF]

Mycoscience, 2021
Obase K, Yamanaka S, Kinoshita A, Tamai Y, Yamanaka T.   +4 more
europepmc   +1 more source

The power of the local in sports broadcasting: a cross-cultural analysis of rugby commentary [PDF]

, 2009
This article explores how local pressures intersect to produce differing broadcasts in 2 cultural contexts. This is achieved via a cross-cultural analysis of a decade of tele¬vised rugby union matches between France and New Zealand and interviews with ...
Bruce, Toni, Desmarais, Fabrice
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Socio-environmental and psychosocial predictors of smoking susceptibility among adolescents with contrasting socio-cultural characteristics: a comparative analysis. [PDF]

BMC Public Health, 2021
Tate C, Kumar R, Murray JM, Sanchez-Franco S, Montgomery SC, Montes F, Dunne L, Sarmiento OL, Kee F, Hunter RF.   +9 more
europepmc   +1 more source

Do Birds of a Feather Flock Together? Immigration Flows and Cultural Clustering in Host Countries [PDF]

This paper presents a simple theoretical framework in which immigrants have a relative incentive to cluster in host countries where cultural characteristics and imperfect information sustain the segmentation of the labor market and a higher wage in ...
Dominique Gross, Nicolas Schmitt
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Book review: Xueliang Ding. (2017).丁學良. Zhengzhi yu zhongguo tese youmo 政治與中國特色幽默 [Politics and Humour with Chinese Characteristics]. Hong Kong: Oxford University Press.

The European Journal of Humour Research, 2020
This is a review of the book Zhengzhi yu zhongguo tese youmo, by Xueliang Ding.
Antonio Leggieri
doaj   +2 more sources