DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Influence of cultural beliefs and practices on unassisted homebirths in Afghanistan: A qualitative exploration. [PDF]
Wassif AR, Najafizada M, Mulay S.
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Addressing communication dynamics in traditional medicine use disclosure to physicians. [PDF]
Gumede L.
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Cross-cultural measurement invariance of the multidimensional competitive orientation inventory: Non-clinical samples in South Korea and Hungary. [PDF]
Aum T, Fülöp M, Kim S, Lee JD, Lee DG.
europepmc +1 more source
Integrating sociocultural theories to inform public health response: unique relationships between moral foundations, cultural cognition worldviews, and COVID-19 attitudes and behaviors. [PDF]
Wolsko C, Marino E.
europepmc +1 more source
Addressing substance use and mental illness among Quinault Indian Nation adolescents and young adults: community perspectives on community and cultural connection. [PDF]
Simon CB +9 more
europepmc +1 more source

