Results 101 to 110 of about 149,666 (298)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Decoding Muslim Cultural Code: Oral Poetic Tradition of the Jbala (Northern Morocco)

Open Theology
Spiritual, sometimes directly imbued and sometimes indirectly suggestive of religiosity, poetic genres are common in all corners of the Arab world. While authored religious poetry in Arabic is fairly well studied, oral, unauthored poetic traditions ...
Gintsburg Sarali
doaj   +1 more source

Sacred topics of Russian cities (12). The image of King David and the visual codes of medieval Vladimir / Сакральная топика русского города (12). Образ Давида и визуальные коды средневекового Владимира

Визуальная теология
The traditional Russian city is not only a rationally planned place of habitation, providing its inhabitants with safety and realization of utilitarian needs, but also a work of urban art, embodying the basic principles of axiologically coloured ...
Sergey Avanesov / Сергей Сергеевич Аванесов
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Cultural differences, information and code systems

, 2002
Cultural differences, information and code ...
S Inthanond (13281618), Konrad Peszynski (13055481), B Corbitt (13278471), T Thanasankit (13278474)   +3 more
core  

The cultural code of Rostov-on-Don in the minds of the media audience

Неофилология
INTRODUCTION. The study is addressed to the cultural code as a modern mechanism for the formation of a value system in the media. The aim of the study was to determine the cultural code of the city of Rostov-on-Don, which is formed by regional media, as ...
A. V. Muha, N. I. Fedoseeva
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Teachers’ and students’ attitudes and practices regarding code switching in writing: A study in selected primary schools in St. Lucia.

, 2011
This study was conducted in three primary schools in St. Lucia, a multilingual country situated in the Caribbean. The goal of this research was to investigate teachers’ and students’ attitudes and practices regarding the use of code switching in the ...
Auguste-Walter, Berthina
core  

Global Street Code. A Cross-cultural Perspective on Youth Violence

, 2019
Kurtenbach S, Zdun S, Howell S, Zaman M, Rauf A. Global Street Code. A Cross-cultural Perspective on Youth Violence. Deviant Behavior. 2019:1-22.Some twenty years ago Anderson's seminal work, The Code of the Street, was published.
Rauf, Abdul, Zaman, Muhammad, Howell, Simon, Zdun, Steffen, Kurtenbach, Sebastian   +4 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source