Results 31 to 40 of about 138,637 (215)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Reconstruction of vanished cities
Проект БайкалThe preservation of historical heritage has the potential to act as a means of regenerative design in line with the concept of sustainable architecture.
Nasirdinova Насирдинова +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Semantics of the Birth Myth as a Cultural Code
RUDN Journal of Language Studies, Semiotics and SemanticsThe study analyzes the birth myth from the symbolic point of view as a way to indicate the beginning of any existence, real or fictional: the birth of the Universe and a man, which sets out the primary understanding of the world and a man, time and space.
Elena S. Stepanova
doaj +1 more source
AMATEUR POETRY FOR THE OCCASIONS: GROUP AXIOLOGICAL VOCABULARY AND CREATIVE SPEECH PRACTICES
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2020 The article presents the results of linguistic, axiological, and stylistic analysis based on the collection of amateur poetry for the occasions “For such a small company...” (2019) published in Yekaterinburg.
Natalia A. Kupina
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Public art in the historical city: Visualizing the local cultural code
Urbis et Orbis: Mikroistoriâ i Semiotika GorodaThe article analyses public art within the framework of the cultural approach – as a form of visualization of the city’s cultural code. The author examines the variants of public art comprehension existing in the Russian academic discourse and identifies
Elizaveta Speshilova
doaj +1 more source
Adeptus, 2015 The concept of cultural codes in Russian and Ukrainian linguoculturological and ethnolinguistic studies This article is an attempt at presenting the concept of cultural codes, which was earlier discussed in works of Russian and Ukrainian scholars in ...
Iryna Chybor
doaj +1 more source
The problem of the cultural code in the sociological dimension
Наука. Культура. Общество, 2020 The author’s idea focuses on the relevance of the problem of recoding the cultural code of the nation and the search for sufficient grounds for its sociological justification.
Zhanna M. Grischenko +1 more
doaj +1 more source