Results 41 to 50 of about 138,637 (215)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Expert interview on the cultural code of Veliky Novgorod: The modernity of the historical city
Urbis et Orbis: Mikroistoriâ i Semiotika GorodaThe expert interview is devoted to the analysis of the cultural code of Veliky Novgorod and to the architectural techniques, which represent it in the urban environment.
Alexey Gavrilov, Elizaveta Speshilova
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
SEARCH FOR «SYNTHESIS OF BEAUTY AND CREATIVITY» IN THE ЕPISTLES OF M. KUZMIN
Вестник Северо-Кавказского федерального университета, 2022 The article presents the messages of one of the most popular poets of the beginning of XX century – M. Kuzmin, in which we can find search for «synthesis of beauty and creativity» which are closely associated with the aesthetic quests of Russian culture ...
Natalia Vladimirovna Protasova
doaj
Sociological Analysis of the Cultural Sector
Социологическая наука и социальная практика, 2017 This article presents theoretical and methodological justification for the sociological analysis of the culture in the modern society. Social studies allow us to analyze the sphere of culture on two different levels: on a symbolic level where the culture
Irina V. Lashuk, Elena V. Taranova
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Translation Properties of Vulgar and Invective Vocabulary in Political Media Discourse
Translation Studies: Theory and PracticeThe present research is an attempt to specify vulgar and invective vocabulary in modern political media discourse and to determine their translation properties (from English into Russian and Armenian, from Russian into English and Armenian, from ...
Gayane Gasparyan, Meri Ishkhanyan
doaj +1 more source
The problems of linguoculturology discussed on the pages of the “Russian Language Studies” journal
Russian Language Studies, 2018 The article presents a review of linguocultural materials published in recent years in the scientific journal “Russian Language Studies” (in the past it was called “The Bulletin of Peoples’ Friendship University of Russia.
Rafael Guzman Tirado
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Lexico-Semantic Transformations in Translation of Stories by V.M. Shukshin into English
RUDN Journal of Language Studies, Semiotics and Semantics, 2019 This article is dedicated to the analysis of a lexico-semantic transformation in translation of fiction. The aim of the paper is to identify frequently and less frequently used translation transformations that we treat as cross-language transformations ...
Svetlana N Vekovishcheva +3 more
doaj +1 more source