Results 61 to 70 of about 138,637 (215)

The phenomenon of Russian quotation: to the problem of methodological research

open access: yesRussian Language Studies
The subject of the study is a Russian quotation from a literary text as part of the intertextual thesaurus of modern youth. The relevance of the study is due to the lack of research on the methodological potential of Russian quotation - a significant ...
Elena R. Yadrovskaya, Alexey I. Dunev
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

RELIGIOUS AND COSMIC: COMPONENTS OF THE SACRED CODE OF CULTURE IN RUSSIAN AND KYRGYZ LANGUAGES [PDF]

open access: yesVestnik Issyk-Kulʹskogo universiteta
In this article, the authors addresses the topic of spiritual shrines of the Kyrgyz and Russian peoples. Religion has always been a deeply intimate part of people's lives.
Kadyrkulova U. K.   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Role of Intertextual Thesaurus in Teacher Professional Training

open access: yesВысшее образование в России
In the educational process, a teacher of any specialization deals with texts in oral and written form and carries out all types of speech activities.
E. R. Yadrovskaya, A. I. Dunev
doaj   +1 more source

The Semantic Space in the Novel of A. Nikolaenko “To kill Bobrykin. The History of one Murder”

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2019
In the article the novel “To kill Bobrykin. The history of one murder” by A. Nikolaenko, the 2017 “Russian Buker” prize-winner, is considered as heterogeneous text.
Nataliia D. Strelnikova
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Cultural Code in Scientific and Journalistic Dimensions

open access: yesНаучный диалог
This article explores the distinctive features of the term “cultural code” within scientific and journalistic discourses. The materials for analysis are drawn from newspaper articles and partially from the main corpus of the Russian National Corpus, as ...
O. A. Dimitrieva
doaj   +1 more source

Liquid intake conceptual metaphor in Russian cultural and linguistic gastronomic code

open access: yesRussian Language Studies, 2018
The paper presents profound findings of figurative linguistic manifestation of the gastronomic code of Russian culture. Lexical and phraseological nominations representing liquid intake conceptual metaphor in Russian are considered in linguocultural and ...
Elena Andreevna Yurina
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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