Results 71 to 80 of about 1,304,530 (293)

Anthroponyms in Chuvash and Russian Riddles About Body Parts: Cultural Codes

open access: yesВестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»
The riddle is a kind of a world model and a way of representing the mentality of a people. Identifying the role of anthroponyms in the structure of a riddle is important for the interpretation of objects of the surrounding reality.
Olga A. Dimitrieva, Tatyana V. Denisova
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Code-switching and dialogism : Verbal practices among Catalan Jews in the Middle Ages [PDF]

open access: yes, 2001
From a strict linguistic viewpoint, code-switching intertwines with a diverse range of language contact phenomena, from strict interference to several kinds of language mixture.
Argenter, Joan A.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A Virtual Laboratory for the Study of History and Cultural Dynamics [PDF]

open access: yes
This article presents a Virtual Laboratory that enables the researcher to try hypothesis and confirm data analysis about different historical processes and cultural dynamics.
Fernando Sancho, Juan-Luis Su�rez
core  

Discourse analysis of corporate codes of ethics : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Accountancy at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2015
Ethics has always been an important element in economic activities. Ethical guidelines in the form of values, beliefs, norms, guidelines and rules have been developed over the years to set boundaries for appropriate business behaviour.
Chua, Frances Cho-Kwai
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Image-Symbol as an Element of the Semiotic System of Artistic Discourse of Ch.T. Aitmatov

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
An image-symbol are examined as key elements of the semiotic system in the stories and novels of Ch.T. Aitmatov. The study of symbolic images helps for deeper understanding of the multidimensional ideological, semantic, moral and emotional content of the
Baktygul T. Diushebekova   +1 more
doaj   +1 more source

Phraseological Units with the Word “Bread” in Russian, Frenchand Italian Linguocultures

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2020
Language is not only a means of communication between people, but also the cultural memory of the speakers of this language. We believe that in linguistic units there is cultural information that indicates the existence of a category that correlates ...
Margarita E. Kaskova   +2 more
doaj   +1 more source

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