Results 71 to 80 of about 131,270 (251)

“The Canterbury Tales” by Geoffrey Chaucer: Classic “Text-code” and Universal Cultural Phenomenon

open access: yesPolylinguality and Transcultural Practices
“The Canterbury Tales”, written over 600 years ago, is considered to be one of the books that changed the world, and its author, the English poet Geoffrey Chaucer, is believed to be the writer who united generations. It is the “Canterbury Tales” that the
Natalia V. Khudolei   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The phenomenon of Russian quotation: to the problem of methodological research

open access: yesRussian Language Studies
The subject of the study is a Russian quotation from a literary text as part of the intertextual thesaurus of modern youth. The relevance of the study is due to the lack of research on the methodological potential of Russian quotation - a significant ...
Elena R. Yadrovskaya, Alexey I. Dunev
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

RELIGIOUS AND COSMIC: COMPONENTS OF THE SACRED CODE OF CULTURE IN RUSSIAN AND KYRGYZ LANGUAGES [PDF]

open access: yesVestnik Issyk-Kulʹskogo universiteta
In this article, the authors addresses the topic of spiritual shrines of the Kyrgyz and Russian peoples. Religion has always been a deeply intimate part of people's lives.
Kadyrkulova U. K.   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Role of Intertextual Thesaurus in Teacher Professional Training

open access: yesВысшее образование в России
In the educational process, a teacher of any specialization deals with texts in oral and written form and carries out all types of speech activities.
E. R. Yadrovskaya, A. I. Dunev
doaj   +1 more source

The Semantic Space in the Novel of A. Nikolaenko “To kill Bobrykin. The History of one Murder”

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2019
In the article the novel “To kill Bobrykin. The history of one murder” by A. Nikolaenko, the 2017 “Russian Buker” prize-winner, is considered as heterogeneous text.
Nataliia D. Strelnikova
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Cultural Code in Scientific and Journalistic Dimensions

open access: yesНаучный диалог
This article explores the distinctive features of the term “cultural code” within scientific and journalistic discourses. The materials for analysis are drawn from newspaper articles and partially from the main corpus of the Russian National Corpus, as ...
O. A. Dimitrieva
doaj   +1 more source

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