Results 81 to 90 of about 7,625,201 (342)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Future Foreign Language Teachers’ Intercultural Competence [PDF]
, 2013 There is a lack of research regarding the implications for foreign language study and intercultural competence. Scholars suggest that foreign language proficiency plays a role in cultivating intercultural competence, but agree that there is a lack of ...
Baalerud, Andrew
core
Cultural competence and the higher education sector: A journey in the academy
, 2020 © The Author(s) 2020. Although cultural competence in higher education is a worthwhile starting point for teaching, learning, research and leadership in the higher education sector, it has been argued that it is the journey and not the destination that ...
Frawley, J +5 more
core +1 more source
Knowledge, skill, and awareness of physiotherapists on cultural competence in southwest Nigeria
Bulletin of Faculty of Physical TherapyBackground Physiotherapists need to be culturally competent to provide effective services to healthcare users of diverse cultures. Here, we investigated the association between selected sociodemographic characteristics and the knowledge, skills, and ...
Joana Adeleke +3 more
doaj +1 more source
BMC Nursing, 2019 BackgroundNowadays, healthcare professionals worldwide deliver care for increasing numbers of culturally and linguistically diverse patients. The importance of cultural competence is evident in terms of the quality of healthcare, and more knowledge is ...
Anu-Maria Kaihlanen +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Cultural competency in the delivery of health services for Indigenous people [PDF]
, 2015 Aim and objectives This review aims to examine available evidence on cultural competence in health care settings to identify key approaches and strategies that can contribute to improving the development and implementation of Indigenous health services ...
K Tsey (9849185) +15 more
core +1 more source
Cultural Competence and Related Factors in Nurses Working in Zahedan Teaching Hospitals: A Cross-Sectional Study [PDF]
تحقیقات سلامت در جامعهIntroduction and Purpose: Cultural competence is one of the most important characteristics that help nurses provide high-quality, equitable healthcare to patients. This study aimed to determine the status of cultural competence and its associated factors
Fatemeh Setoodehzadeh +3 more
doaj +3 more sources