Results 61 to 70 of about 1,066,703 (287)

Smoke and Mirrors: The National Lottery and the Non-Profit Sector [PDF]

, 2002
In a context of massive reductions in government consumption spending, the National Lottery is intended to provide a sustainable source of funding for non-profit organisations providing much needed sporting, arts, cultural, social and environmental ...
Stephen Louw
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

An international review of cultural consumption research [PDF]

Despite the effects of the crisis, several studies show that there has been an increase in cultural production in all the most important western countries over the last twenty years.
Anna Moretti, Francesco Casarin
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Culture Talk in Capitalist Realism: How We Talk about Culture and Why It's Important

Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Соціологічні дослідження сучасного суспільства: методологія, теорія, методи, 2020
The article is devoted to the study of the phenomenon of everyday practice of culture talk, the search for the most appropriate sociological optics for the study of this phenomenon.
Konstantin Belozyorov
doaj   +1 more source

CULTURAL CONSUMPTION AS PART OF THE COLOMBIAN INCOME 1999-2004 [PDF]

Plenty of people’s consumption is referred to necessary products used every day, and the cultural products are classified as sumptuary groceries used aside the people’s basic necessities.
Adriana Lozano, Camilo Herrera, Fabian Garcia   +2 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Analyzing cultural routes from a multidimensional perspective

Almatourism, 2011
The objective of this work is to examine cultural routes from a multidimensional and hence a multidisciplinary perspective. Economic impacts and geographical sides are the most studied aspects.
Wided Majdoub
doaj   +1 more source

Impact Model of Tourism Production and Consumption in Nanjing Yunjin: The Perspective of Cultural Heritage Reproduction [PDF]

, 2020
Ke Zhang, Mu Zhang, Rob Law, Xuanyu Chen, Qiongyao Wang   +4 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source