Results 41 to 50 of about 5,572,091 (300)

Provisión eficiente de bienes públicos: oferta y demanda de bibliotecas públicas en Colombia

Revista Finanzas y Política Económica, 2023
The present research aims to carry out a study on the supply of public libraries in Colombia and the variables that determine their demand. To analyze the supply, the Directory of public libraries carried out by the National Library of Colombia is used,
Doris Lilia Andrade Agudelo, Angy Lorena Fernández-Cantero, Dayana Andrea Velásquez-Galeano.   +2 more
doaj  

Usos del tiempo y consumo cultural de los estudiantes universitarios

CPU-e, 2013
El trabajo analiza la baja participación estudiantil en las diversas actividades artístico-culturales de la Universidad Veracruzana. Desde un enfoque sociológico, reflexiona acerca de los Consumos Culturales de las/os jóvenes universitarias/os ...
Dra. Marcela País Andrade
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

“National Cultural Elements” and Advertising the International Tourism in the Soviet Tourist Agencies During the Brezhnev Era, 1964–1984

Sprawy Narodowościowe. Seria nowa, 2022
“National Cultural Elements” and Advertising the International Tourism in the Soviet Tourist Agencies During the Brezhnev Era, 1964–1984 Using the archival documents and personal interviews as historical sources, this essay analyzes the ideological ...
Sergei Zhuk
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Cultural Mobilization During the Special Military Operation: How “New” Ethics Changes “Old” Habits

Регионология
Introduction. In Russia, after the start of the Special Military Operation in Ukraine, large-scale transformations accelerated, affecting all spheres of activity, including cultural consumption practices.
Natalia V. Zhadunova, Ekaterina A. Koval, Sergey G. Ushkin, Andrey A. Sychev   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source