Results 61 to 70 of about 470,545 (264)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Implementation of Positive and Negative Politeness Strategies in Kazakh and Russian Family Discourse Talk Show

RUDN Journal of Language Studies, Semiotics and Semantics
The research material was talk-shows presented on the YouTube platform. The study is aimed at identifying the characteristics of the use of polite strategies in different cultural contexts and their impact on communication within the family. Attention is
Nazerke Yergazy, Anastasia V. Denisenko
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Toplumsal Yarar Amaçlı Örgütlerin Farklı Kültürlerdeki Instagram Paylaşımları Üzerine Bir Analiz: Türkiye ve İngiltere’deki Greenpeace Örneği

Online Academic Journal of Information Technology, 2018
Toplumsal yarar amaçlı örgütlerin temel amacı toplumda ortak bilgi ve dil düzeyi oluşturarak kolektif bilincin ve eylemin oluşmasına aracılık etmektir.
Gamze Yetkin Cılızoğlu
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Russian Specialists’ Perception of Negotiations with Chinese Partners: Expectations, Strategies and Challenges

RUDN Journal of Psychology and Pedagogics
In the context of global challenges and changing geopolitical situations around the world, Russian organizations are increasingly facing the necessity of active cooperation with countries in the Far East, especially China. The purpose of this exploratory
Ekaterina D. Vasilyeva, Albina A. Gallyamova, Elizaveta Sh. Komyaginskaya, Nadezhda M. Lebedeva   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

How culture influences perspective taking: Differences in correction, not integration

Frontiers in Human Neuroscience, 2013
Individuals from East Asian (Chinese) backgrounds have been shown to exhibit greater sensitivity to a speaker's perspective than Western (US) participants when resolving referentially ambiguous expressions. We show that this cultural difference does
Shali eWu, Dale J Barr, Timothy Matthew Gann, Boaz eKeysar   +3 more
doaj   +1 more source