Results 61 to 70 of about 2,308,358 (256)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cultural Pluralism and Epistemic Injustice [PDF]

, 2019
For liberalism, values such as respect, reciprocity, and tolerance should frame cultural encounters in multicultural societies. However, it is easy to disregard that power differences and political domination also influence the cultural sphere
Collste, Göran
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Destini raccontati: quando la narratologia incontra l’interculturalismo

Comparatismi, 2016
Negli ultimi decenni, gli studi condotti da un numero crescente di psicologi sociali e neuroscienziati hanno riscontrato che una visione del Sé come autonomo e indipendente è maggiormente diffusa nelle aree euro-nordamericane, mentre una visione del Sé ...
Valentina Conti
doaj   +1 more source

Schools and civil society : corporate or community governance [PDF]

, 2012
School improvement depends upon mediating the cultural conditions of learning as young people journey between their parochial worlds and the public world of cosmopolitan society.
Arendt H., Arendt H., Arendt H., Balarin M., Ball S.J., Barton V., Bentley T., Black, A, Cohen J., DCSF, DCSF, DCSF, Dean C., Deem R., Department for Children, Schools and Families (DCSF), Department for Education and Schools (DfES), Department for Education and Science (DES), DES, DES, DES, DfE S., DfE S., DfE S., DfE S., DfE S., DfE S., DfEE, Earley P., Ferguson A., Fullan M., Gellner E., Hann C., Hasan R., Haskins Report, Hegel G., Keane J., Keane J., Keane J., Lingard B., Lord P., Marx K., Moll L., Mouzelis N., Newsom P., Pelcyzynski Z.A., PricewaterhouseCoopers, Raab C., Ranson S., Ranson S., Rhodes R., Riedel M., Siep L., Stewart Ranson, Walzer M., Wells G., Whitfield D., Woods P.   +56 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The impact of industry group culture on the development of opportunism in cross-sector alliances [PDF]

, 2008
Over the last two decades the world economy has dramatically transformed, with strategic alliances and partnerships across industrial and global boundaries becoming an important means to maintaining and regaining competitive positioning.
Grant, SB
core  

Cultural differences in intimacy: The influence of gender-role ideology and individualism-collectivism [PDF]

, 2008
Two studies examined emotional intimacy in European Canadian and Chinese Canadian dating relationships. Cultural differences in gender-role ideology and individualism–collectivism were hypothesized to differentially contribute to selfdisclosure and ...
Altman, I., Berry, J.W., Dion, K.K., Jack, D.C., Jourard, S.M., Lebra, T.S., Lin, Y.C., Liu, C.-L.J., Loscocco, K.A., Matsumoto, D., Prager, K.J., Tara C. Marshall   +11 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source