Results 71 to 80 of about 470,545 (264)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
THE IMPACT OF MANAGERIAL MULTICULTURAL COMPETENCES ON COMPANY’S COMPETITIVE ADVANTAGE IN GLOBAL ECONOMY [PDF]
Innovative Issues and Approaches in Social Sciences, 2014 In this article, we will present an empirical account on management of intercultural differences. The focus will be on managerial dilemma how to achieve the company’s competitiveness with adaptation to market forces as well as to the cultural environment
Rosana Grušovnik, Dejan Jelovac
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
COMPARATIVE ANALYSIS ON EASTERN AND CENTRAL EUROPEAN STUDENTS’ INTERCULTURAL SENSITIVITY. RESEARCH CONDUCTED IN ROMANIA, HUNGARY AND SLOVENIA [PDF]
Journal of Languages for Specific Purposes, 2016 The following study is meant to be an extension of and completion to a former research paper entitled “The Role of Foreign Language Teachers in Developing Students’ Intercultural Communication Skills” concluding that students of the University of Oradea,
Hamburg Andrea
doaj
Cultural Relativism, Cultural Difference
, 2017 Cultural relativism, like cultural absolutism or cultural pluralism, refers to a theoretical system for classifying and understanding human variation. The concept of cultural relativism emerged as a set of descriptive and epistemological precepts within American anthropology in the late nineteenth and early twentieth centuries and, more broadly, in the
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Consumers’ responses to CSR in a cross-cultural setting
Cogent Business & Management, 2015 The paper aims to clarify the relationship between corporate social responsibility (CSR) and consumer behaviour in an international setting. Consumers’ responses to CSR activities and the impact on the purchase decision are limited discourses.
Hakan Karaosman +2 more
doaj +1 more source