Results 91 to 100 of about 168,693 (266)

Cultural dimensions of individualism and collectivism and risk of opioid misuse: A test of Social Cognitive Theory. [PDF]

J Clin Psychol, 2022
Kim SY, Park SY, Mathai B, Daheim J, France C, Delgado B.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

A Comparative Study on the Cultural Dimensions and Health Perception of the COVID-19 Pandemic between China and the United States. [PDF]

Healthcare (Basel), 2022
Zhang Y, Liu S, Jun J.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Explaining People's Worry Levels During the Covid-19 Pandemic: An Analysis of Socio-Economic and Cultural Dimensions. [PDF]

Front Psychol, 2021
Rojas-Méndez JI.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Medical Students' and Trainees' Country-By-Gender Profiles: Hofstede's Cultural Dimensions Across Sixteen Diverse Countries. [PDF]

Front Med (Lausanne), 2021
Monrouxe LV, Chandratilake M, Chen J, Chhabra S, Zheng L, Costa PS, Lee YM, Karnieli-Miller O, Nishigori H, Ogden K, Pawlikowska T, Riquelme A, Sethi A, Soemantri D, Wearn A, Wolvaardt L, Yusoff MSB, Yau SY.   +17 more
europepmc   +1 more source

Language and culture in dimension

Domínios de Lingu@gem, 2021
Onomastic studies in general—and the studies of the onomastic systems of indigenous languages in particular—require interdisciplinary investigations that address properly the diversity inherent in the field. In this vein, the present work discusses how linguistic concepts dialogue with anthropology and ethnography in the study of the onomastic system ...
Tereza Tayná Coutinho Lopes, Marília Ferreira   +1 more
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Kültürün Reklamlar Üzerindeki Etkileri Perspektifinden Renault “Hayat Kadar Beklenmedik” Örneğine Göstergebilimsel Bir Bakış

Erciyes İletişim Dergisi
Kültür bir toplumun asırlık birikimiyle oluşmaktadır. Kültürel farklılıklar bazen bir törende, bazen bir kelimede, bazen bir yemekte bile gözlemlenebilmektedir.
Semih Kopuz, Metin Işık, Ebru Yılmaz
doaj   +1 more source