Results 71 to 80 of about 186,206 (267)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Characteristics of the Romanian Entrepreneurial Prototype [PDF]
Revista de Management Comparat International, 2011 The objective of this paper is to portray the Romanians’ entrepreneurial current prototype, following to their cultural background and entrepreneurial education – as result of the authors’ own research, and compared to previous similar studies.
Cezar SCARLAT +2 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Cultural Dimension of Image Readability
Journal of Visual Literacy, 2000 Abstract. The paper focuses on the role that cultural bias plays in lowering the readability of an instructional illustration. Taking theoretical frameworks by Lantz (1996) and Mody (1991) as a point of departure, the various approaches that the producer of an illustration can follow in order to reduce culturally based readability barriers are ...
openaire +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The effects of cultural dimensions on export performance: Vietnam and Colombia cases. [PDF]
Heliyon, 2022 Escandon-Barbosa D, Salas-Paramo J.
europepmc +1 more source
The National Cultural Dimensions of Lithuania
Ekonomika, 2002 This paper introduces the results of national cultural dimensions of potential Lithuanian managers, according to Hofstede’s indices. It will be seen that Lithuanians scored high on Masculinity, and average on Uncertainty Avoidance, Individualism and Power Distance, relative to all other countries in the database. These results are discussed in terms of
openaire +3 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The Correlation between Hofstede's Cultural Dimensions and COVID-19 Data in the Early Stage of the COVID-19 Pandemic Period. [PDF]
Healthcare (Basel), 2023 Chang LH, Wu S.
europepmc +1 more source