Results 121 to 130 of about 5,569,454 (345)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Cultural dimensions in online learning

open access: yes, 2005
The increase of competitiveness in the higher education global market demands many universities to find innovative approaches in providing education services.
Djojosaputro, L.   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Geographical Proximity is not Enough: How Culture Shaped Placement, Spatiality, and the Outcomes of the Arab Spring’s Uprising

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2017
This paper investigates the phenomenon of the Arab Spring against the background of cultural traditions and attitudes that sustained these protests and carried them across borders of more than twenty countries in the Middle East in a move of cultural ...
Olesya Venger
doaj  

Medical Students' and Trainees' Country-By-Gender Profiles: Hofstede's Cultural Dimensions Across Sixteen Diverse Countries. [PDF]

open access: yesFront Med (Lausanne), 2021
Monrouxe LV   +17 more
europepmc   +1 more source

THE APPLICABILITY OF STRATEGIC ANALYSIS METHODS FOR COMPETITION ENVIRONMENT IN THE DIAGNOSIS OF CULTURAL ORGANIZATION IN REGIONAL CONTEXT [PDF]

open access: yes
Culture has various dimensions, from instrument of communication and promotion of national values and expression of the national spirit to ways of spending free time.
Razvan-Andrei CORBOS
core  

National Culture\u27s Impact on Effectiveness of Supply Chain Disruption Management [PDF]

open access: yes, 2016
The purpose of this research is to understand the national cultural antecedents that may help explain differences in supply chain disruptions mitigation abilities of companies from different countries.
Demirag, Ozgun C.   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Editorial: Back to the Future—Predicting Possibilities in Open, Flexible, and Distance Learning

open access: yesJournal of Open, Flexible and Distance Learning, 2015
In 2010 Ako Aotearoa, the national centre for tertiary teaching excellence, prompted DEANZ, our national association for open, flexible, and distance learning, to look towards the future in 2016.
Maggie Hartnett   +2 more
doaj   +2 more sources

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