Results 131 to 140 of about 1,567,848 (355)
National cultures and European integration: exploratory essays on cultural diversity and common policies [PDF]
, 1995 Erik Holm
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
The impact of student diversity in secondary schools: An analysis of the international PISA data and implications for the German education system [PDF]
While increased heterogeneity in schools (diversity) leads to reduced segregation and greater equity for students from different family backgrounds, it is often expected to have a negative impact on overall performance, and on student well-being and ...
Bourdon, Jean, Michaelowa, Katharina
core
Bridging cultural binaries through pedagogical practices [PDF]
, 2013 In internationalising the curriculum, the move away from polarising domestic and international students to focus on preparing all students for global citizenship is promising.
Meerwald, A.M.L.
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Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Cultural clash and educational diversity: Immigrant teachers' efforts to rescue the education of immigrant children in Israel [PDF]
, 2000 Alek D. Epstein, Nina G. Kheimets
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The Diversion of Culture, the Politics of Cultural Geography
GEOgraphia, 2014 Nas décadas de 1980 e 1990, uma nova geografia cultural emergiu, prioritariamente como uma resposta à proeminência que o marxismo e da economia política haviam assumido no campo da Geografia desde a década de 1970, mas também como um reflexo mudanças sociais mais amplas do capitalismo avançado.
openaire +3 more sources