Results 91 to 100 of about 768,673 (305)

The fourth year : building on the foundations: 1991-92 annual report [PDF]

open access: yes, 1992
This booklet represents the fourth annual report on the partnership program between Simon Fraser University and the Secwepemc Cultural Education Society, covering the 1991-92 Academic Year.

core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Evaluating the Effectiveness of Cultural Education Training: Cultural Competence and Cultural Intelligence Development among Nursing Students. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Majda A   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Socio-economic and cultural mediators of mathematics achievement and between-school equity in mathematics education at the global level [PDF]

open access: yes, 2014
This paper aims at identifying and understanding how and to what extent socioeconomic and cultural factors mediate mathematics achievement and between-school equity in mathematics education among countries.
Jurdak, Murad Eid
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

YOLOv10-CBRC: A high-precision document image layout analysis model

open access: yesJournal of King Saud University: Computer and Information Sciences
Tibetan document layout analysis (DLA) is a crucial aspect of the digitization of Tibetan documents. However, two significant issues persist: (1) the inadequacy of Tibetan document datasets;(2) insufficient utilization of layout information by existing ...
Zhenjie Wu, Weilan Wang, Hongrui Li
doaj   +1 more source

Cultural pollution among students of the College of Education for Girls

open access: yesالأستاذ, 2018
The cultural pollution problem era because girls universities are more influenced by what is happening in their communities Baattabarhn most receptive to what surrounds them of the threats and dangers of the girls while they may not have the decision ...
Prof. Dr.. Sacrificed Adel Mahmoud   +2 more
doaj   +1 more source

Policy on technical and vocational education and training: Technical and vocational education and training for economic advancement

open access: yes, 1993
This policy paper articulates a major development plan for the further development and efficient and effective delivery of technical and vocational education and training.
Guyana. Ministry of Education and Cultural Development
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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