Results 51 to 60 of about 464,088 (258)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Bridging worlds: a study of academic skills, cultural exchange, and integration in UK higher education

open access: yesJournal of Learning Development in Higher Education
This case study explores the experience of an Academic Skills Adviser and an international postgraduate student at a university in the North West of England in relation to academic skills, cultural exchange, and integration into higher education in the ...
Anthony D. Cliffe, Lin Chou
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Candle Symbolisms in the Sinulog Dance Vis-à-vis the Exploration of the Kahayag Model of Reflective Teaching

open access: yesDiversitas Journal
Understanding the symbolism of candles in the Sinulog dance is essential to the devotional practices of Catholic Christians. The study described the symbolism of candles in the Sinulog dance, explored how this tradition continued, and examined potential
Erica Marie Aray   +4 more
doaj   +1 more source

Kurikulum Pendidikan Budaya pada Satuan Pendidikan Rintisan

open access: yesJurnal Pendidikan dan Kebudayaan, 2013
This study aims to obtain a picture related to the implementation of the cultural curriculum development efforts 300 units on preschool education, primary education, secondary education, exceptional education, and educational equality that has been ...
Sutjipto --
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Learning while Traveling: Influences of Short-term Cross-cultural Immersion Experiences to High School Students

open access: yesDiversitas Journal
This present study explored the experiences of Filipino learner-participants in a 6-day cross-cultural immersion held in Indonesia, aiming to understand how they interpreted their cultural learning over a year later.
Bernadette Bugtong
doaj   +1 more source

Authenticity and brain health: a values-based perspective and cultural education approach. [PDF]

open access: yesFront Neurol, 2023
Stirland LE   +3 more
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

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