Results 121 to 130 of about 6,392,593 (355)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Compound and Incorporation Constructionsas Combinations of Unexpandable Roots

open access: yesZeitschrift für Wortbildung
This paper offers definitions of the terms compound construction, compoundand incorporation constructionthat can be applied to all languages in the same way.
Martin Haspelmath
doaj   +1 more source

Cultural selection and biased transformation: two dynamics of cultural evolution

open access: yesPhilosophical Transactions of the Royal Society of London. Biological Sciences, 2021
A. Mesoudi
semanticscholar   +1 more source

A bibliometric analysis of the interdisciplinary field of cultural evolution

open access: yesPalgrave Communications, 2018
The science of cultural evolution is unified in its application of evolutionary logic to socially transmitted behavior, but diverse in methodologies and assumptions. Qualitative reviews have encouraged integration by illuminating points of divergence and
Mason Youngblood, D. Lahti
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Rationalization enables cooperation and cultural evolution

open access: yesBehavioral and Brain Sciences, 2018
Cushman argues that the function of rationalization is to attribute mental representations to ourselves, thereby making these representations available for future planning. I argue that such attribution is often not necessary and sometimes maladaptive. I
Neil L Levy
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Exact Solutions for Network Rewiring Models

open access: yes, 2007
Evolving networks with a constant number of edges may be modelled using a rewiring process. These models are used to describe many real-world processes including the evolution of cultural artifacts such as family names, the evolution of gene variations ...
Evans, T. S.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Allelic Variation at the Rht8 Locus in a 19th Century Wheat Collection

open access: yesThe Scientific World Journal, 2012
Wheat breeding during the 20th century has put large efforts into reducing straw length and increasing harvest index. In the 1920s an allele of Rht8 with dwarfing effects, found in the Japanese cultivar “Akakomugi,” was bred into European cultivars and ...
Linnéa Asplund   +2 more
doaj   +1 more source

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