Results 201 to 210 of about 6,748,108 (328)

Historicizing the liberal antiracism of Cultural Evolution. [PDF]

Hist Philos Life Sci
Brinitzer C.
europepmc   +1 more source

The Cultural Evolution of Medical Technologies : A Model of Sequential Treatments in the Medical Setting. [PDF]

Hum Nat, 2023
Hong Z.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The neural underpinnings of repeated skill transfer in human cultural evolution. [PDF]

Front Psychol
Øhrn H, Sjursen EP, Specht K, Hugdahl K, Straffon LM, Bender A.   +5 more
europepmc   +1 more source

The importance of thinking about the future in culture and cumulative cultural evolution. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2022
Vale GL, Coughlin C, Brosnan SF.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The cultural evolution of distortion in music (and other norms of mixed appeal). [PDF]

Philos Trans R Soc Lond B Biol Sci
Bryant GA, Smaldino PE.
europepmc   +1 more source

Human socio-cultural evolution in light of evolutionary transitions: introduction to the theme issue. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Carmel Y, Shavit A, Lamm E, Szathmáry E.   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Half a century of quantitative cultural evolution. [PDF]

Proc Natl Acad Sci U S A
Fogarty L, Kandler A, Creanza N, Feldman MW.   +3 more
europepmc   +1 more source